Methods for preventing or reducing colon carcinogenesis

Patent metadata

Field	Value
Publication number	US-9913817-B2
Application number	US-201615088654-A
Country	US
Kind code	B2
Filing date	Apr 1, 2016
Priority date	Dec 5, 2008
Publication date	Mar 13, 2018
Grant date	Mar 13, 2018

Abstract

The present invention is directed in part to methods of preventing or reducing colon carcinogenesis comprising administering to a patient at risk of colorectal cancer, a pharmaceutical preparation comprising disclosed chemopreventive. In another aspect, the invention is directed to methods attenuation of oxygen free radicals comprising administrating to a patient in need thereof an antioxidant effective amount of a compound represented by formula I, IIa or IIb as disclosed herein.

First claim

We claim:

1. A method of treating psoriasis, the method comprising administering orally to a patient in need thereof an effective amount of 2-methoxy-3-(4′-aminophenyl) propionic acid, or a pharmaceutically acceptable salt or a stereoisomer thereof.

2. The method of claim 1 , wherein the stereoisomer is (S)-2-methoxy-3-(4′-aminophenyl) propionic acid, or a pharmaceutically acceptable salt thereof.

Assignees

• Nogra Pharma Ltd

Inventors

• Baroni Sergio
• Bellinvia Salvatore
• Viti Francesca

Classifications

• A61P9/10

  for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis · CPC title

• A61P5/14

  of the thyroid hormones, e.g. T3, T4 · CPC title

• A61P37/00

  Drugs for immunological or allergic disorders · CPC title

• A61P9/02

  Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives · CPC title

• A61P39/06

  Free radical scavengers or antioxidants · CPC title