Medical device having a surface comprising nanoparticles

Patent metadata

Field	Value
Publication number	US-9889237-B2
Application number	US-201313875355-A
Country	US
Kind code	B2
Filing date	May 2, 2013
Priority date	May 11, 2012
Publication date	Feb 13, 2018
Grant date	Feb 13, 2018

Abstract

A medical device has a surface intended for contact with living tissue, wherein the surface comprises nanoparticles comprising a non-toxic post-transition metal such as gallium and/or bismuth, said nanoparticles having an average particle size of 500 nm or less. The nanoparticles may provide an antimicrobial effect, and thus the risk for infection may be reduced.

First claim

The invention claimed is:

1. A medical device, which is a dental implant intended for implantation at least partially into living tissue, said dental implant comprising a non-bioresorbable substrate having a surface intended for contact with living tissue, wherein the surface includes a homogenous monolayer of nanoparticles comprising titanium dioxide, bismuth nitride, and gallium nitride, the monolayer of nanoparticles having a thickness from 100 nm to 400 nm with said nanoparticles having an average particle size of 500 nm or less.

2. The medical device according to claim 1 , wherein said nanoparticles of titanium dioxide have an average particle size of 100 nm or less.

3. The medical device according to claim 1 , wherein said medical device comprises a substrate having said surface, which substrate comprises a metal or an alloy.

4. The medical device according to claim 3 , wherein said substrate comprises titanium, zirconium, hafnium, vanadium, niobium, tantalum, cobalt or iridium, or an alloy thereof.

5. The medical device according to claim 1 , wherein the dental implant is a dental fixture intended to be inserted at least partially into living bone tissue.

6. The medical device according to claim 1 , wherein the dental implant is a dental abutment, intended to be in contact with living soft tissue.

7. A method of implanting a medical device into the living body of a human or animal, the method comprising:
a) providing a medical device according to claim 1 ; and
b) implanting said medical device into said living body of a human or animal, wherein the medical device is positioned such that at least part of the surface comprising nanoparticles comprising a non-toxic post-transition metal is in contact with living tissue.

Assignees

• Dentsply Int Inc
• Dentsply Sirona Inc

Inventors

• Arvidsson Anna
• Mattisson Ingela
• Ahlberg Elisabet
• Loeberg Johanna

Classifications

• A61L27/306

  Other specific inorganic materials not covered by A61L27/303 - A61L27/32 · CPC title

• A61L27/02

  Inorganic materials · CPC title

• A61L27/30

  Inorganic materials · CPC title

• A61C8/00 Primary

  Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools (fastening of peg-teeth in the mouth A61C13/30) · CPC title

• A61L2430/12

  for dental implants or prostheses · CPC title