Compositions with reduced bitter taste perception

Patent metadata

Field	Value
Publication number	US-9827320-B2
Application number	US-201514633161-A
Country	US
Kind code	B2
Filing date	Feb 27, 2015
Priority date	Feb 27, 2014
Publication date	Nov 28, 2017
Grant date	Nov 28, 2017

Abstract

A composition with reduced bitterness containing polyquaternium-2, polyquaternium-17, and/or polyquaternium-18.

First claim

What is claimed is:

1. An ingestible composition with reduced bitterness comprising from about 0.0001% to about 0.001% of a polyquaternium selected from the group consisting of polyquaternium-2, polyquaternium-17, polyquaternium-18, and combinations thereof, wherein the composition is selected from the group consisting of bitter foods, bitter beverages, and combinations thereof, and wherein overall bitterness is reduced by at least about 25% as compared to an identical composition without the polyquaternium, as determined by the in vitro Assay for Taste Receptors.

2. The ingestible composition of claim 1 wherein an overall bitterness is reduced by at least about 40% as compared to an identical composition without the polyquaternium as determined by the in vitro Assay for Taste Receptors.

3. The ingestible composition of claim 1 wherein an overall bitterness is less than about 7000 fluorescence units as determined by the in vitro Assay for Taste Receptors.

4. The ingestible composition of claim 1 wherein an overall bitterness is less than about 5000 fluorescence units as determined by the in vitro Assay for Taste Receptors.

5. An ingestible composition with reduced bitterness comprising:
a. from about 0.0001% to about 0.001% of a polyquaternium selected from the group consisting of polyquaternium-2, polyquaternium-17, polyquaternium-18, and combinations thereof; and
b. a bitter component selected from the group consisting of Hops, guaifenesin, phenytoin, omeprazole, cetirizine, jambu, acetaminophen, methyl formyl anthranilate, 2-aminoacetophenone, beta-terpineol, beta-naphthyl anthranilate, benzoyl anthranilic acid, 1,10-phenanthroline, saccharin, benzamide, brucine, and combinations thereof.

6. The ingestible composition of claim 5 wherein the composition is selected from the group consisting of bitter foods, bitter beverages, medications, oral care compositions, and combinations thereof.

7. The ingestible composition of claim 5 wherein an overall bitterness is reduced by at least about 40% as compared to an identical composition without the polyquaternium as determined by the in vitro Assay for Taste Receptors.

8. The ingestible composition of claim 5 wherein an overall bitterness is less than about 7000 fluorescence units as determined by the in vitro Assay for Taste Receptors.

9. The ingestible composition of claim 5 wherein an overall bitterness is less than about 5000 fluorescence units as determined by the in vitro Assay for Taste Receptors.

10. The ingestible composition of claim 5 further comprising a sweetener.

11. The ingestible composition of claim 5 further comprising from about 2% to about 25% of a sweetener.

Assignees

• Procter & Gamble

Inventors

• Lin Yakang
• Sreekrishna Koti

Classifications

• A61Q11/00

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title

• A61K2800/5426

  cationic · CPC title

• A61K8/84 Primary

  obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds · CPC title

• A61K47/34 Primary

  Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers (A61K47/10 takes precedence) · CPC title

• A23L27/86

  Addition of bitterness inhibitors · CPC title