Flexible biopsy collection device and related methods of use

Patent metadata

Field	Value
Publication number	US-9770228-B2
Application number	US-201514817696-A
Country	US
Kind code	B2
Filing date	Aug 4, 2015
Priority date	Jul 13, 2005
Publication date	Sep 26, 2017
Grant date	Sep 26, 2017

Abstract

Embodiments of the invention are directed to a medical device and methods for collecting a tissue sample from a patient's body. The device may include a first tube defining a lumen and an aperture at a distal end of the first tube. A second tube extends within the lumen of the first tube and defines a lumen and slots, where at least some of the slots have sharp edges configured to shear tissue. The second tube is movable relative to the first tube such that the sharp edges cut a plurality of samples from tissue disposed within the aperture.

First claim

What is claimed is:

1. A method of collecting a tissue sample, comprising:
inserting a medical device into a body, the medical device comprising:
a first flexible tube defining a lumen and an aperture at a distal end of the first tube, wherein a distal tip of the first tube covers an entirety of a distalmost portion of the lumen of the first tube, and
a second flexible tube extending within the lumen of the first tube, the second tube defining (i) a lumen, (ii) a pattern of slots arranged to provide flexibility to the second tube such that the second tube is configured for lateral deflection, wherein at least two slots of the pattern of slots are offset circumferentially from each other around a circumference of the second tube, and (iii) a cutting edge configured to shear tissue; and

axially moving the second tube relative to the first tube to cut tissue disposed within the aperture.

2. The method of claim 1 , wherein at least a portion of slots of the second tube extend in a spiral pattern along the second tube, and wherein inserting the medical device into the body includes flexing a region of the second tube along the spiral pattern.

3. The method of claim 1 , further comprising:
laterally deflecting the medical device; and
positioning the distal end of the first tube at a sample collection site such that the aperture receives the tissue.

4. The method of claim 3 , wherein the slots have sharp edges, and axially moving the second tube relative to the first tube causes the sharp edges of the slots to cut multiple samples from the tissue disposed within the aperture.

5. The method of claim 1 , further comprising:
rotating the second tube relative to the first tube.

6. The method of claim 1 , further comprising:
positioning the aperture of the first tube to receive the tissue;
receiving the tissue within the aperture;
sliding the second tube distally within the first tube until the cutting edge of the second tube is proximal of the aperture of the first tube; and
moving the second tube distally relative to the first tube such that the cutting edge shears the tissue received within the aperture.

7. The method of claim 6 , wherein the cutting edge is distal facing, and wherein moving the second tube distally relative to the first tube includes moving the second tube until the cutting edge of the second tube is distal of the aperture of the first tube.

8. The method of claim 6 , wherein a distal end of the second tube is open, and wherein moving the second tube distally relative to the first tube includes moving the second tube until the cutting edge of the second tube is distal of the aperture of the first tube.

9. The method of claim 8 , further comprising:
suctioning the sheared tissue through the lumen of the second tube.

10. A method of collecting a tissue sample, comprising:
inserting a medical device into a body, the medical device comprising:
a first flexible tube defining a lumen and an aperture at a distal end of the first tube; and
a second flexible tube extending within the lumen of the first tube, the second tube defining a lumen and a plurality of slots spaced along a length of the second tube, wherein a first subset of the plurality of slots located in a distal region of the second tube includes a cutting edge, and a second subset of the plurality of slots located proximal to the distal region does not include a cutting edge;

positioning the distal end of the first tube at a sample collection site such that the aperture receives tissue to be collected; and
moving the second tube relative to the first tube such that a sharp edge of the second tube cuts at least one sample from the received tissue.

11. The method of claim 10 , wherein a distal end of the second tube is open, the sharp edge of the second tube is a distal facing cutting edge disposed along a perimeter of the open distal end, and wherein moving the second tube relative to the first tube includes moving the second tube distally within the first tube until the cutting edge of the second tube is distal of the aperture of the first tube.

12. The method of claim 11 , wherein moving the second tube relative to the first tube includes shearing the tissue received within the aperture with the cutting edge.

13. The method of claim 10 , wherein a side surface at a distal end of the second tube defines an opening forming the sharp edge, the method further comprising:
receiving the tissue within the opening; and
rotating the second tube to cut the tissue.

14. The method of claim 10 , wherein the plurality of slots are arranged to provide flexibility to the second tube such that the second tube is configured for lateral deflection, the method further comprising:
laterally deflecting the second tube.

15. A method of collecting a tissue sample in the body, comprising:
inserting a medical device into the body, the medical device comprising:
a first flexible tube defining a lumen and an aperture at a distal end of the first tube, wherein a distal tip of the first tube covers an entirety of a distalmost portion of the lumen of the first tube; and
a second flexible tube extending within the lumen of the first tube, wherein the second tube includes a pattern of slots extending along a distal region of the second tube, wherein at least two slots of the pattern of slots are offset circumferentially from each other around a circumference of the second tube;

positioning the distal end of the first tube at a sample collection site such that the aperture receives tissue to be collected; and
moving the second tube relative to the first tube such that at least one sharp edge of the second tube cuts at least one sample from the tissue disposed within the aperture.

16. The method of claim 15 , further comprising:
suctioning the at least one sample through a lumen of the second tube.

17. The method of claim 15 , wherein a distal end of the second tube is open and includes the at least one sharp edge, wherein the at least one sharp edge is a distal facing cutting blade along a perimeter of the open distal end, and the distal facing cutting blade is moved relative to the aperture of the first tube to cut the at least one sample.

18. The method of claim 15 , wherein the pattern of slots includes at least one slot having a cutting edge, and moving the second tube relative to the first tube cuts multiple samples from the tissue.

19. The method of claim 15 , wherein a side surface at a distal end of the second tube defines an opening forming the at least one sharp edge, the method further comprising:
receiving the tissue within the opening;
rotating the second tube relative to the first tube; and
cutting the sample positioned within the opening.

20. The method of claim 15 , wherein the pattern of slots is arranged to provide flexibility to the second tube, and wherein inserting a medical device into the body includes laterally deflecting the second tube.

Assignees

• Boston Scient Scimed Inc

Inventors

• Chin Yem
• Devries Robert
• Scopton Paul
• Hutchins John

Classifications

• A61B2017/2905

  flexible · CPC title

• A61B2010/0225

  for taking multiple samples · CPC title

• A61B10/0283

  with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe (A61B10/025, A61B10/0266 take precedence) · CPC title

• A61B10/0275 Primary

  with sample notch, e.g. on the side of inner stylet · CPC title