Flexible biopsy collection device and related methods of use

Patent metadata

Field	Value
Publication number	US-9125638-B2
Application number	US-17964005-A
Country	US
Kind code	B2
Filing date	Jul 13, 2005
Priority date	Jul 13, 2005
Publication date	Sep 8, 2015
Grant date	Sep 8, 2015

Abstract

Embodiments of the invention are directed to a medical device and methods for collecting a tissue sample from a patient's body. The device may include a first tube defining a lumen and an aperture at a distal end of the first tube. A second tube extends within the lumen of the first tube and defines a lumen and slots, where at least some of the slots have sharp edges configured to shear tissue. The second tube is movable relative to the first tube such that the sharp edges cut a plurality of samples from tissue disposed within the aperture.

First claim

What is claimed is:

1. A medical device, comprising:
a first tube defining a lumen and an aperture at a distal end of the first tube, the aperture facing a first side of the first tube, the first tube further defining a plurality of discrete slots proximal the aperture and facing a second side of the first tube opposite the first side, wherein each of the discrete slots includes a passageway extending completely through the second side of the first tube, wherein a distal tip of the first tube covers an entirety of a distalmost portion of the lumen of the first tube; and
a second tube extending within the lumen of the first tube, the second tube defining a lumen and slots, at least some of the slots of the second tube having sharp edges configured to shear tissue, wherein adjacent slots of the second tube are longitudinally spaced from each other along a longitudinal axis of the second tube;
wherein the second tube is configured for lateral deflection, and wherein the second tube is movable relative to the first tube such that the sharp edges cut a plurality of samples from tissue disposed within the aperture.

2. The medical device of claim 1 , further comprising a drive connected to the second tube configured to provide movement of the second tube relative to the first tube.

3. The medical device of claim 2 , wherein the drive moves the second tube relative to the first tube with rotary movement.

4. The medical device of claim 1 , wherein the second tube moves axially relative to the first tube.

5. The medical device of claim 4 , wherein axial movement of the second tube relative to the first tube causes the sharp edges of the slots of the second tube to cut the plurality of samples from tissue.

6. The medical device of claim 1 , wherein the aperture is defined by a side surface of the first tube.

7. The medical device of claim 1 , wherein the first tube defines multiple apertures along a side surface of the first tube.

8. The medical device of claim 1 , wherein the slots of the second tube extend transverse to the longitudinal axis of the second tube.

9. The medical device of claim 1 , wherein the slots of the second tube extend only partially through a wall forming the second tube.

10. The medical device of claim 1 , wherein at least a portion of slots of the second tube extend in a spiral pattern along the second tube.

11. The medical device of claim 1 , wherein at least one of the first and second tube is electronically conductive and configured to act as an electrode for conducting current to tissue.

12. The medical device of claim 1 , wherein a proximal end of the second tube is connected to a vacuum source that provides suction within the lumen of the second tube.

13. The medical device of claim 1 , further comprising a tissue collection receptacle connected to a proximal end of the second tube.

14. The medical device of claim 1 , wherein a distal end of the second tube is open and includes a distal facing cutting blade along a perimeter of the open distal end, wherein the distal facing cutting blade is moved relative to the aperture of the first tube to cut a sample from material disposed within the aperture.

15. The medical device of claim 1 , wherein a side surface at the distal end of the second tube defines an aperture forming a cutting blade configured to cut a tissue sample upon rotation of the second tube within the first tube when tissue is positioned within the apertures defined by the first and second tubes.

16. The medical device of claim 1 , further comprising a deflection control wire configured for laterally deflecting the first and second tubes.

17. The medical device of claim 1 , wherein the slots of the second tube form a pattern of transverse beams and axial beams.

18. The medical device of claim 1 , wherein the slots of the second tube are arranged along opposite sides of the second tube.

19. The medical device of claim 1 , wherein the plurality of discrete slots of the first tube includes slots arranged along opposite sides of the first tube.

20. The medical device of claim 1 , wherein the plurality of discrete slots of the first tube are arranged transverse a longitudinal axis of the first tube and include axially adjacent slots and radially adjacent slots, the axially adjacent slots defining transverse beams, and the radially adjacent slots defining axial beams.

21. The medical device of claim 1 , wherein the distal tip includes a sharp tip configured to penetrate tissue.

22. A method of collecting a tissue sample in a body, comprising:
inserting a medical device into the body, the medical device comprising:
a first tube defining a lumen and an aperture at a distal end of the first tube, the aperture facing a first side of the first tube, the first tube further defining a plurality of discrete slots proximal the aperture and facing a second side of the first tube opposite the first side, wherein each of the discrete slots includes a passageway extending completely through the second side of the first tube, wherein a distal tip of the first tube covers an entirety of a distalmost portion of the lumen of the first tube; and
a second tube extending within the lumen of the first tube, the second tube defining a lumen and slots, at least some of the slots of the second tube having sharp edges, wherein adjacent slots of the second tube are longitudinally spaced from each other along a longitudinal axis of the second tube;

inserting the medical device into the body such that the medical device is laterally deflected during insertion;
positioning a distal end of the first tube at a sample collection site such that the aperture receives tissue to be collected; and
moving the second tube relative to the first tube such that the sharp edges of the slots of the second tube cut multiple samples from the tissue disposed within the aperture.

23. The method of claim 22 , wherein moving the second tube relative to the first tube comprises reciprocating the second tube axially relative to the first tube.

24. The method of claim 22 , wherein moving the second tube relative to the first tube comprises rotating the second tube relative to the first tube.

25. The method of claim 22 , further comprising collecting the samples at a proximal end of the second tube.

26. The method of claim 22 , further comprising providing suction within the lumen of the second tube.

27. The method of claim 22 , wherein the aperture is defined by a side surface of the first tube.

28. The method of claim 22 , wherein the first tube defines multiple apertures along a side surface of the first tube.

29. The method of claim 22 , wherein the slots of the second tube extend transverse to the longitudinal axis of the second tube.

30. The method of claim 22 , wherein the slots of the second tube extend only partially through a wall forming the second tube.

31. The method of claim 22 , wherein at least a portion of slots of the second tube extend in a spiral pattern along the second tube.

32. The method of claim 22 , further comprising:
repositioning the distal end of the first tube at an additional sample collection site without removing the medical device from the body, such that the aperture receives tissue to be collected; and
moving the second tube relative to the first tube such that the s

Assignees

• Chin Yem
• Devries Robert
• Scopton Paul
• Hutchins John
• Boston Scient Scimed Inc

Inventors

• Chin Yem
• Devries Robert
• Scopton Paul
• Hutchins John

Classifications

• A61B2017/2905

  flexible · CPC title

• A61B2010/0225

  for taking multiple samples · CPC title

• A61B10/0283

  with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe (A61B10/025, A61B10/0266 take precedence) · CPC title

• A61B10/0275 Primary

  with sample notch, e.g. on the side of inner stylet · CPC title