Deposition of discrete nanoparticles on an implant surface

Patent metadata

Field	Value
Publication number	US-9763751-B2
Application number	US-201313934385-A
Country	US
Kind code	B2
Filing date	Jul 3, 2013
Priority date	Nov 14, 2005
Publication date	Sep 19, 2017
Grant date	Sep 19, 2017

Abstract

A dental implant made of a material comprising titanium. The implant includes a head portion having a non-rotational feature, a lowermost end opposing the head portion, and a threaded bottom portion for engaging bone between the head portion implant and the lowermost end. The implant further includes a nanocrystalline surface formed on at least a portion of the implant. The nanocrystalline surface includes discrete nanocrystals deposited on a roughened surface of the implant. The roughened surface includes at least one of a grit-blasted surface or an acid-etched surface. A portion of the roughened surface is exposed between at least some of the discrete nanocrystals such that the exposed roughened portion between the discrete nanocrystals is capable of contacting bone.

First claim

What is claimed is:

1. A dental implant made of a material comprising titanium comprising:
a head portion having a non-rotational feature;
a lowermost end opposing the head portion;
a threaded bottom portion for engaging bone between the head portion and the lowermost end; and
discrete nanocrystals deposited on a roughened surface of the implant, the roughened surface including at least one of a grit-blasted surface and an acid-etched surface, wherein a portion of the roughened surface is exposed between at least some of the discrete nanocrystals such that the exposed roughened portion between the discrete nanocrystals is capable of contacting bone.

2. The dental implant of claim 1 , wherein the nanocrystals comprise a material that promotes osseointegration.

3. The dental implant of claim 1 , wherein the implant is made of commercially pure titanium.

4. The dental implant of claim 1 , wherein the discrete nanocrystals include hydroxyapatite nanocrystals having dimensions on the order of about 20 nanometers to about 100 nanometers.

5. The dental implant of claim 1 , wherein the roughened surface includes titanium hydroxide and/or titanium oxide.

6. The dental implant of claim 5 , wherein the discrete nanocrystals are directly bonded to the titanium hydroxide and/or titanium oxide.

7. The dental implant of claim 1 , wherein the roughened surface that receives the discrete nanocrystals is free of an alkoxide and a tri-functional silane.

8. A dental implant made of a material comprising titanium comprising:
a head portion having a non-rotational feature;
a lowermost end opposing the head portion;
a threaded bottom portion for engaging bone between the head portion and the lowermost end, the threaded bottom portion including titanium hydroxide and/or titanium oxide positioned over at least one of a grit blasted surface and an acid-etched surface of the implant; and
discrete hydroxyapatite nanocrystals deposited thereon, the titanium hydroxide and/or titanium oxide being exposed between at least some of the discrete hydroxyapatite nanocrystals such that both the exposed portion of the titanium oxide and the hydroxyapatite nanocrystals are capable of contacting bone.

9. The dental implant of claim 8 , wherein the hydroxyapatite nanocrystals are deposited by exposing the at least one of the grit blasted surface and the acid-etched surface to a solution including the hydroxyapatite nanocrystals.

10. The dental implant of claim 8 , wherein the threaded bottom portion has a grit blasted roughened surface with an array of microscale irregularities.

11. The dental implant of claim 10 , wherein the irregularities have peak-to-valley heights not greater than about 20 microns.

12. The dental implant of claim 8 , wherein the discrete hydroxyapatite nanocrystals are directly bonded to the titanium hydroxide and/or titanium oxide.

13. The dental implant of claim 8 , wherein the discrete hydroxyapatite nanocrystals have dimensions on the order of about 20 nanometers to about 100nanometers.

14. The dental implant of claim 8 , wherein the at least one of the grit blasted surface and the acid-etched surface that receives the discrete hydroxyapatite nanocrystals is free of an alkoxide or a tri-functional silane.

15. A dental implant made of a material comprising titanium comprising:
a head portion having a non-rotational feature;
a lowermost end opposing the head portion; and
a threaded bottom portion for engaging bone between the head portion and the lowermost end, the threaded bottom portion having a grit blasted roughened surface with an array of microscale irregularities, the threaded bottom portion further including discrete hydroxyapatite nanoparticles deposited directly on the grit blasted roughened surface, wherein a portion of the grit blasted roughened surface is exposed between at least some of the discrete hydroxyapatite nanoparticles such that the exposed roughened portion between the discrete hydroxyapatite nanoparticles is for contacting bone.

16. The dental implant of claim 15 , wherein the discrete hydroxyapatite nanoparticles cover less than all of the grit blasted roughened surface.

17. The dental implant of claim 15 , wherein the grit blasted roughened surface includes titanium hydroxide and/or titanium oxide.

18. The dental implant of claim 17 , wherein the discrete hydroxyapatite nanoparticles are directly bonded to the titanium hydroxide and/or titanium oxide.

19. The dental implant of claim 15 , wherein the hydroxyapatite nanoparticles are on the order of about 20 nanometers to about 100 nanometers.

20. The dental implant of claim 15 , wherein the implant is made of commercially pure titanium.

Assignees

• Biomet 3I Llc

Inventors

• Berckmans Iii Bruce
• Towse Ross W
• Mayfield Robert L

Classifications

• C23C22/03

  containing phosphorus compounds · CPC title

• A61K6/84

  comprising metals or alloys · CPC title

• A61K6/838

  Phosphorus compounds, e.g. apatite · CPC title

• A61F2310/00017

  Iron- or Fe-based alloys, e.g. stainless steel · CPC title

• C23C26/00

  Coating not provided for in groups C23C2/00 - C23C24/00 · CPC title