Device for a biological liquid treatment installation

Patent metadata

Field	Value
Publication number	US-9739424-B2
Application number	US-201414493858-A
Country	US
Kind code	B2
Filing date	Sep 23, 2014
Priority date	Jun 8, 2010
Publication date	Aug 22, 2017
Grant date	Aug 22, 2017

Abstract

The invention concerns a device comprising:
a base ( 2 ); a moveable or removable door ( 20 ), said device having a closed door position; and in the closed door position, a circuit ( 8 ) comprising a bag comprising two flexible films and conveying network connectors, and a press ( 9 ) comprising a first shell ( 16 ) disposed on said front face ( 5 ) of said base ( 2 ) and a second shell ( 17 ) disposed in said door ( 20 ); said bag being clamped between said first shell ( 16 ) and said second shell ( 17 ) in a state in which conduits of said network for conveying liquid are formed between said films.

First claim

The invention claimed is:

1. A method of treating biological fluids, comprising:
providing a source of a biological fluid;
providing a source of a treatment component;
providing a device comprising:
a base having a front face;
a moveable or removable door, said device having a closed door position; and
in the closed door position, a circuit comprising a plurality of connectors and a network for conveying liquid between said connectors, which circuit comprises a bag comprising two flexible films and said conveying network connectors, which circuit further comprises a press comprising a first shell disposed on said front face of said base and a second shell disposed in said door, said first and second shells each being of a solid block of rigid material;

said bag being clamped between said first shell and said second shell in a state in which conduits of said network for conveying liquid are formed between said films;
connecting at least one of said connectors to said source of said biological fluid;
connecting at least one of said connectors to said source of a treatment component; and
introducing said biological fluid into said device.

2. The method of claim 1 , further comprising inflating said bag, causing a first of said two flexible films to conform to the face of said first shell and the second of said two flexible films to conform to the face of said second shell.

3. The method of claim 1 , further comprising:
disconnecting said source of said biological fluid and said source of a treatment component from said connectors;
removing said bag from said device; and
connecting a second bag to said source of biological fluid and to a second treatment component.

4. The method of claim 1 , wherein said source of a treatment component comprises valves to allow or prevent the passage of said liquid in said conduits.

5. The method of claim 1 , further comprising providing a sensor to measure physico-chemical values of said biological fluid.

6. The method of claim 1 , further comprising providing a plurality of interchangeable modules, each module comprising a first shell, a second shell and a bag.

7. The method of claim 1 , wherein said device has a position other than said closed door position in which said bag is carried only by the first shell.

Assignees

• Emd Millipore Corp

Inventors

• Cirou Sebastien
• Reinbigler Rene
• Buisson Virginie
• Weissenbach Jean-Louis

Classifications

• C12M47/12

  Purification (C12M47/04 takes precedence) · CPC title

• F04B43/08

  having tubular flexible members (F04B43/12 takes precedence) · CPC title

• Y10T137/8593

  Systems · CPC title

• B01D2313/125

  Discharge manifolds · CPC title

• Y10T137/0318

  Processes · CPC title