Device for a biological liquid treatment installation

Patent metadata

Field	Value
Publication number	US-9259733-B2
Application number	US-201314413555-A
Country	US
Kind code	B2
Filing date	Jul 18, 2013
Priority date	Jul 23, 2012
Publication date	Feb 16, 2016
Grant date	Feb 16, 2016

Abstract

The invention concerns a device comprising a circuit comprising a bag ( 10 ) comprising two flexible films ( 65, 66 ), a press ( 9 ) comprising a first shell ( 16 ) disposed upright on a front face of a base of the device and a second shell ( 17 ) mounted on said first shell, which shells clamp said bag to form conduits ( 13 ); said press is provided with a system ( 170 ) for jamming at the location of a treatment zone ( 67 ) of the bag, which comprises a jamming member ( 171 ) provided with at least one jamming nipple ( 173 ) and a complementary jamming member ( 172 ) provided with a jamming channel ( 174 ) configured to receive said nipple; said jamming member ( 171 ) and complementary jamming member ( 172 ) and said bag ( 10 ) being configured in order for the latter to have a portion ( 175 ) in said treatment zone in which said films are jammed between said nipple and said channel.

First claim

The invention claimed is:

1. A device for a biological liquid treatment installation, comprising a base having a front face, and a circuit comprising a plurality of connectors and a network for conveying liquid between said connectors, which circuit comprises a bag comprising two flexible films and said conveying network connectors, which circuit further comprises a press comprising a first shell disposed upright on said front face of said base and a second shell mounted on said first shell, said first shell and second shell cooperating with said bag to form, between said flexible films, by clamping of said bag between said first shell and said second shell, conduits of said conveying network; the two said flexible films of said bag being joined to each other and delimiting a treatment zone for said liquid according to a closed outline, said conveying network connectors emerging on the inside and on the outside of at least one side of said outline;
wherein said press is provided with a system for jamming said bag at the location of said treatment zone thereof, said jamming system comprising at least one jamming member for jamming said bag and at least one complementary jamming member for jamming said bag, said at least one jamming member being provided with at least one jamming nipple and said at least one complementary jamming member being provided with at least one jamming channel configured to receive said at least one jamming nipple; said at least one jamming member, said at least one complementary jamming member and said bag being configured in order for the latter to have at least one portion in said treatment zone in which said films are jammed between said at least one jamming nipple and said at least one jamming channel.

2. A device according to claim 1 , wherein said at least one jamming member is fastened in a first recessed accommodation of said first shell and said at least one complementary jamming member is fastened in a second recessed accommodation of said second shell.

3. A device according to claim 2 , wherein said at least one jamming member and said at least one complementary jamming member are disposed facing said treatment zone and in immediate proximity to a plurality of conduits of said routing network.

4. A device according to claim 2 , wherein said at least one jamming member and said at least one complementary jamming member are each disposed in a similar position to that of said first shell on said front face of said base.

5. A device according to claim 2 , wherein said at least one jamming member is provided with a plurality of jamming nipples distributed longitudinally, regularly or irregularly, on a front wall of said at least one jamming member.

6. A device according to claim 2 , wherein said at least one complementary jamming member is provided with a single jamming channel formed longitudinally in a main opening of said at least one complementary jamming member.

7. A device according to claim 2 , wherein said bag comprises first through apertures on one side of said bag for its positioning, and said first shell comprises studs for hooking said bag to an upper part of said first shell, said hooking studs being configured to pass through said first through apertures of said bag .

8. A device according to claim 2 , wherein said second shell has a first hole, said bag comprises at least one second through aperture in said treatment zone and said device comprises a press locking system configured such that it locks said first shell and second shell together, which system is provided with at least one ball-lock pin having an unlocked state and a locked state, said ball-lock pin being fastened to said first shell, being configured to pass through said first shell and said second through aperture and to emerge in said first hole of said second shell, where said ball-lock pin is furthermore configured to be free therein in said unlocked state and to be fastened therein in said locked state.

9. A device according to claim 2 , wherein said bag comprises at least one third through aperture on one side of said bag, said first shell comprises at least one dowel pin configured to pass through said third through aperture, and said second shell comprises at least one second hole configured to receive said dowel pin of said first shell.

10. A device according to claim 2 , further comprising a movable or removable door, said device having a closed door position, in which second shell is disposed in said door to form said circuit and which furthermore has a position other than said closed door position, in which said bag is carried only by the first shell.

11. A device according to claim 10 , further comprising a hinge system hinging said door relative to said base, said hinge system being disposed only on one side of said door so as to form, in the closed door position, lateral clearances between said door and said base over the rest of a perimeter of said door, so as to enable free access to the connectors of said bag.

12. A device according to claim 2 , wherein said circuit comprises instruments necessary for the treatment of said biological liquid, said instruments selected from the group consisting of valves to allow or prevent the passage of said liquid in said conduits, and sensors of physico-chemical values of said liquid, and wherein said instruments are integrated into said first shell.

13. A device according to claim 4 , wherein said at least one jamming member and said at least one complementary jamming member are each disposed in a substantially vertical, or in a position perpendicular to that of said first shell on said front face, or in an intermediate inclined position.

14. A device according to claim 1 , wherein said at least one jamming member is of parallelepiped general shape provided with a front wall from which projects said at least one jamming nipple.

15. A device according to claim 14 , wherein said at least one complementary jamming member is of parallelepiped general shape provided with a main opening in which is provided said at least one jamming channel.

16. A device according to claim 15 , wherein said at least one jamming nipple has a flared base and a straight wall remote from said flared base, and said at least one jamming channel has a back wall and flared edges.

17. A device according to claim 1 , wherein said at least one jamming member and said at least one complementary jamming member are disposed facing said treatment zone and in immediate proximity to a plurality of conduits of said routing network.

18. A device according to claim 1 , wherein said at least one jamming member and said at least one complementary jamming member are each disposed in a similar position to that of said first shell on said front face of said base.

19. A device according to claim 18 , wherein said at least one jamming member and said at least one complementary jamming member are each disposed in a substantially vertical, or in a position perpendicular to that of said first shell on said front face, or in an intermediate inclined position.

20. A device according to claim 1 , wherein said at least one jamming member is provided with a plurality of jamming nipples distributed longitudinally, regularly or irregularly, on a front wall of said at least one jamming member.

21. A device according to claim 1 , wherein said at least one complementary jamming member is provided with a single jamming channel formed longitudinally in a main opening of said at least one complementary jamming member.

Assignees

• Emd Millipore Corp

Inventors

• Tuccelli Ronald
• Cirou Sebastien
• Buisson Virginie
• Abouayad El Idrissi Christine
• Kelly Jim

Classifications

• B01L2300/0816

  Cards, e.g. flat sample carriers usually with flow in two horizontal directions · CPC title

• Y10T137/9029

  With coupling · CPC title

• B01L2400/0655

  pinch valves · CPC title

• B01L3/561 Primary

  Tubes; Conduits · CPC title

• B01L3/565

  Seals · CPC title