System for blood separation with gravity valve for controlling a side-tapped separation chamber

Patent metadata

Field	Value
Publication number	US-9737898-B2
Application number	US-201514850295-A
Country	US
Kind code	B2
Filing date	Sep 10, 2015
Priority date	Jun 13, 2011
Publication date	Aug 22, 2017
Grant date	Aug 22, 2017

Abstract

A disposable blood separation set and a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having an inlet, a primary outlet and a side tap outlet adjacent the inlet. A valve that is responsive to centrifugal force (a “gravity” valve) selects between the outlet and the side tap outlet. The gravity valve is mounted on the rotor. When the rotor spins at high speed, the gravity valve may open the primary outlet and close the side tap outlet. When the rotor spins at a lower speed, the gravity valve may open the side tap outlet and close the primary outlet.

First claim

What is claimed is:

1. A disposable blood separation set comprising
a circumferential blood processing chamber adapted to be mounted on a centrifuge rotor;
an inlet line fluidly connected to said blood processing chamber;
a generally frustro-conical cell separation chamber in fluid communication with said blood processing chamber and adapted to be mounted on said centrifuge rotor;
the cell separation chamber having an inlet and a primary outlet, said inlet being fluidly connected to said blood processing chamber,
a side tap outlet on said cell separation chamber, said side tap outlet being adjacent said inlet,
a first outlet line fluidly coupled to said primary outlet,
a second outlet line fluidly coupled to said side tap outlet, and
a common outlet line, said first and second outlet lines being fluidly coupled to said common outlet line adjacent said cell separation chamber at a junction, and
a sheath surrounding at least said inlet line and said outlet line, wherein said junction is between said cell separation chamber and said sheath.

2. The disposable blood separation set of claim 1 wherein said inlet protrudes into said cell separation chamber.

3. The disposable blood separation set according to claim 2 wherein said protruding inlet has a generally frustro-conical inner surface that slants radially outwardly from said inlet to a mouth of said protruding inlet, said mouth opening into said separation chamber.

4. The disposable blood separation set of claim 2 wherein said cell separation chamber further comprises a circumferential well between said protruding inlet and said inner wall and wherein said side tap outlet opens into said well.

5. The disposable blood separation set of claim 1 wherein each of said common outlet line is fluidly connected to an extracorporeal tubing circuit.

Assignees

• Terumo Bct Inc

Inventors

• Holmes Brian M
• Ladtkow James R

Classifications

• B01D21/262

  by using a centrifuge · CPC title

• A61M1/30

  Single needle dialysis {; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis} · CPC title

• B04B2005/045

  having annular separation channels · CPC title

• A61M1/308

  Volume control, e.g. with open or flexible containers, by counting the number of pump revolutions, weighing · CPC title

• A61M1/303

  having a reservoir for treated blood to be returned · CPC title