Interface for ion source and vacuum housing

Patent metadata

Field	Value
Publication number	US-9721774-B2
Application number	US-201415023099-A
Country	US
Kind code	B2
Filing date	Sep 17, 2014
Priority date	Sep 20, 2013
Publication date	Aug 1, 2017
Grant date	Aug 1, 2017

Abstract

A mass spectrometer or ion mobility spectrometer is disclosed comprising: an ion block for receiving ions; a heater for heating the ion block; a vacuum housing; and an interface block arranged between the ion block and the vacuum housing; wherein the interface block is formed from a polymer. The polymer interface block inhibits the heat transfer from the ion block to the vacuum housing and also electrically isolates the ion block and vacuum housing. The interface block further comprises at least one conduit through the body of the interface block. This enables gas to be transmitted through the interface block to the ion block, and also enables the interface block to be cooled.

First claim

The invention claimed is:

1. A mass spectrometer or ion mobility spectrometer comprising:
an ion block for receiving ions;
a heater for heating the ion block;
a vacuum housing; and
an interface block arranged between the ion block and the vacuum housing;
wherein the interface block is formed from a polymer;
wherein the interface block comprises an axial conduit extending through it for allowing ions to pass from the ion block into the vacuum housing; and
wherein the interface block further comprises at least one conduit through the body of the interface block for transmitting gas through the interface block to the ion block.

2. The spectrometer of claim 1 , wherein the ion block is mounted to one side of the interface block and/or the vacuum housing is mounted to an opposing side of the interface block.

3. The spectrometer of claim 1 , wherein the vacuum housing comprises at least one conduit through its body for supplying gas to said at least one conduit in the interface block and/or wherein the ion block comprises at least one conduit for receiving gas from said at least one conduit in the interface block.

4. The spectrometer of claim 1 , wherein the polymer interface block is arranged and configured to thermally insulate the vacuum housing from the ion block.

5. The spectrometer of claim 1 , wherein the material forming the interface block has a thermal conductivity selected from the group consisting of: <0.7 W/m.° C.; <0.6 W/m.° C.; <0.5 W/m.° C.; <0.4 W/m.° C.; <0.3 W/m.° C.; <0.2 W/m.° C.; <0.1 W/m.° C.; or 0.01 to 0.5 W/m.° C.

6. The spectrometer of claim 1 , wherein the interface block is formed from PEEK.

7. The spectrometer of claim 1 , wherein the polymer interface block is arranged and configured to electrically isolate the ion block from the vacuum housing.

8. The spectrometer of claim 1 , wherein an ion guide formed from electrodes is arranged in said axial conduit for guiding ions.

9. The spectrometer of claim 1 , wherein the vacuum housing comprises at least one of the following: ion optics; an ion mass analyser; an ion mobility analyser; or an ion trap.

10. The spectrometer of claim 1 , wherein the vacuum housing and/or the ion block is substantially formed from metal.

11. The spectrometer of claim 1 , further comprising an ion source enclosure having a cavity therein which houses an ion source, wherein the source enclosure is mounted to the interface block such that the cavity is arranged over and encloses the ion block.

12. The spectrometer of claim 11 , wherein the inner surface of said cavity is metallic and wherein the source enclosure is mounted to the interface block such that the metallic inner surface is spaced apart from the vacuum housing by the interface block.

13. The spectrometer of claim 11 , wherein a polymer buffer element is mounted to the ion block and arranged and configured to engage an inner surface of the source enclosure cavity so as to space the inner surface of the source enclosure from the ion block.

14. The spectrometer of claim 1 , wherein the spectrometer comprises a miniature mass spectrometer or a miniature ion mobility spectrometer.

15. The spectrometer of claim 1 , wherein the interface block comprises a groove or handle for use in removing the interface block from the vacuum housing.

16. The spectrometer of claim 1 , wherein electronics for powering said heater pass through a conduit in said interface block to said heater.

17. A method of mass spectrometry or ion mobility spectrometry conducted with a spectrometer comprising an ion block for receiving ions; a heater for heating the ion block; a vacuum housing; and an interface block arranged between the ion block and the vacuum housing; wherein the interface block is formed from a polymer; wherein the interface block comprises an axial conduit extending through it for allowing ions to pass from the ion block into the vacuum housing; and wherein the interface block further comprises at least one conduit through the body of the interface block for transmitting gas through the interface block to the ion block, said method comprising:
heating the ion block with said heater,
transmitting ions from said ion block, through said axial conduit in said interface block and into said vacuum housing; and
analysing said ions with an analyser arranged in said vacuum housing.

18. The method of claim 17 , comprising supplying a gas to the ion block through said at least one conduit in the body of the interface block.

19. The method of claim 18 , comprising supplying said gas through at least one conduit in the body of said vacuum housing and into said at least one conduit in the interface block; and/or receiving said gas from said at least one conduit in the interface block in at least one conduit within the ion block.

20. The method of claim 17 , comprising:
using the polymer interface block to thermally insulate a high temperature component on one side of the interface block from a low temperature component on the opposite side of the interface block; and/or
using the polymer interface block to electrically insulate a high voltage component on one side of the interface block from a low voltage component on the opposite side of the interface block.

21. The method of claim 17 , comprising guiding ions through said axial conduit in an ion guide formed from electrodes.

Assignees

• Micromass Ltd

Inventors

• Hess Anthony
• O'Brien Steve
• Trivett Ian

Classifications

• H01J49/044

  with means for preventing droplets from entering the analyzer; Desolvation of droplets · CPC title

• H01J49/0031

  Step by step routines describing the use of the apparatus (H01J49/0081 takes precedence) · CPC title

• H01J49/10

  Ion sources; Ion guns · CPC title

• H01J49/02 Primary

  Details · CPC title

• H01J49/049

  with means for applying heat to desorb the sample; Evaporation · CPC title