Powdered nutritional composition with large lipid globules

Patent metadata

Field	Value
Publication number	US-9700073-B2
Application number	US-201415035387-A
Country	US
Kind code	B2
Filing date	Nov 7, 2014
Priority date	Nov 11, 2013
Publication date	Jul 11, 2017
Grant date	Jul 11, 2017

Abstract

The invention pertains to powdered nutritional compositions comprising large lipid globules and micronized carbohydrate or carbohydrate microcrystals. Preferably the nutritional composition is an infant or follow on formula or a growing up milk. The invention also pertains to the use of micronized carbohydrate or carbohydrate microcrystals for improving flow and reducing cohesiveness of a powdered nutritional composition with large lipid globules.

First claim

The invention claimed is:

1. A powdered nutritional composition comprising protein, carbohydrates and
(a) lipid globules with a volume weighted mode diameter of 1 micrometer or above and/or at least 45 volume % based on total lipid with a diameter of 2 to 12 micrometer; and
(b) micronized carbohydrates (i) being smaller than 30 micrometer, and/or (ii) of which at least 80 volume % has a size less than 20 micrometer, and/or (iii) of which at least 80 volume % has a size less than 10 micrometer, and/or (iv) having a volume median particle size D50 below 10 micrometer, wherein 35-55% of the total energy content of the composition is derived from lipid, 5-12.5% of the total energy content of the composition is derived from protein, and 40-55% of the total energy content of the composition is derived from carbohydrates comprising digestible carbohydrates, wherein at least 35 wt % of the digestible carbohydrate is lactose.

2. The powdered nutritional composition according to claim 1 , wherein the micronized carbohydrates comprise micronized lactose, micronized glucose, micronized maltodextrin, micronized starch, micronized inulin, micronized sucrose, or a combination thereof.

3. The powdered nutritional composition according to claim 2 , wherein the micronized carbohydrates comprise micronized lactose.

4. The powdered nutritional composition according to claim 1 , wherein (iii) at least 80 volume % of the micronized carbohydrates have a size less than 10 micrometer, and/or (iv) the micronized carbohydrates have a volume median particle size D50 below 10 micrometer.

5. The powdered nutritional composition according to claim 1 , comprising 1-30 wt %, based on total weight of the composition, of the micronized carbohydrates.

6. The powdered nutritional composition according to claim 5 , comprising 2-20 wt %, based on total weight of the composition, of the micronized carbohydrates.

7. The powdered nutritional composition according to claim 6 , comprising 2-10 wt %, based on total weight of the composition, of the micronized carbohydrates.

8. The powdered nutritional composition according to claim 1 , having a Flodex flowability index of at least 30.

9. The powdered nutritional composition according to claim 8 , having a Flodex flowability index of at least 45.

10. The powdered nutritional composition according to claim 1 , being an infant formula, a follow on formula, and/or a growing up formula.

11. The powdered nutritional composition according to claim 1 , wherein the composition comprises 10 to 50 wt % lipid based on the weight of the nutritional composition.

12. The powdered nutritional composition according to claim 1 , comprising at least 0.5 wt % phospholipids based on total lipid; and/or comprising protein derived from bovine milk.

13. The powdered nutritional composition according to claim 1 , wherein the lipid globules have a volume-weighted mode diameter between 2.0 and 10 micrometer.

14. The powdered nutritional composition according to claim 13 , wherein the lipid globules have a volume-weighted mode diameter between 4.0 micrometer and 8.0 micrometer.

15. The powdered nutritional composition according to claim 11 , wherein at least 45 volume % of the lipid globules has a diameter between 2 and 12 micrometer.

16. A method for manufacturing a powdered nutritional composition, comprising
(a) obtaining a spray-dried powder comprising proteins, lipids and carbohydrates, vitamins and micronutrients, and having lipid globules with a volume weighted mode diameter of 1 micrometer or above and/or at least 45 volume % based on total lipid have a diameter of 2 to 12 micrometer,
(b) blending the powder with micronized carbohydrates
(i) smaller than 30 micrometer, and/or
(ii) at least 80 volume % of which has a size less than 20 micrometer, and/or
(iii) at least 80 volume % of which has a size less than 10 micrometer, and/or
(iv) having a volume median particle size D50 below 10 micrometer.

17. The method according to claim 16 , wherein the micronized carbohydrates comprise micronized lactose, micronized glucose, micronized maltodextrin, micronized starch, micronized inulin, micronized sucrose, or a combination thereof.

18. The method according to claim 17 , wherein the micronized carbohydrates are (iii) at least 80 volume % of which has a size less than 10 micrometer, and/or have (iv) a volume median particle size D50 below 10 micrometer.

19. A method for providing nutrition to a subject in need thereof, the method comprising:
(a) reconstituting powdered nutritional composition comprising protein, carbohydrates and
(i) lipid globules with a volume weighted mode diameter of 1 micrometer or above and/or at least 45 volume % based on total lipid with a diameter of 2 to 12 micrometer; and
(ii) micronized carbohydrates (A) being smaller than 30 micrometer, and/or (B) of which at least 80 volume % has a size less than 20 micrometer, and/or (C) of which at least 80 volume % has a size less than 10 micrometer, and/or (D) having a volume median particle size D50 below 10 micrometer,
wherein 35-55% of the total energy content of the composition is derived from lipid 5-12.5% of the total energy content of the composition is derived from protein, and 40-55% of the total energy content of the composition is derived from carbohydrates comprising digestible carbohydrates, wherein at least 35 wt % of the digestible carbohydrate is lactose, and

(b) administering the reconstituted composition to the subject.

20. The method according to claim 19 , wherein the subject is a human child below 3 years of age.

21. The method according to claim 19 , wherein the micronized carbohydrates are present in an amount of 0.5-30 wt %.

22. The method according to claim 19 , wherein the reconstituted composition has a caloric densities between 0.1 and 2.5 kcal/ml.

23. The method according to claim 19 , wherein the reconstituted composition has a viscosity between 1 and 100 mPa·s at a shear rate of 95 s −1 at 20° C.

24. A method for providing nutrition to a subject in need thereof, the method comprising:
(a) reconstituting powdered nutritional composition comprising:
(i) protein,
(ii) lipid globules with a volume weighted mode diameter of 1 micrometer or above and/or at least 45 volume % based on total lipid with a diameter of 2 to 12 micrometer;
(iii) digestible carbohydrates, wherein at least 35 wt % of the digestible carbohydrates is lactose;
(iv) micronized carbohydrates (A) being smaller than 30 micrometer, and/or (B) of which at least 80 volume % has a size less than 20 micrometer, and/or (C) of which at least 80 volume % has a size less than 10 micrometer, and/or (D) having a volume median particle size D50 below 10 micrometer, and

(b) administering the reconstituted composition to the subject.

25. A method for providing nutrition to a subject in need thereof, the method comprising:
(a) reconstituting powdered nutritional composition comprising:
(i) protein,
(ii) lipid globules with a volume weighted mode diameter of 1 micrometer or above and/or at least 45 volume % based on total lipid with a diameter of 2 to 12 micrometer;
(iii) fat, comprising at least 0.5 wt % LCPUFAs with 20-22 C atoms, with at least 80 wt % being the combination of EPA and DHA;
(iv) micronized carbohydrates (A) being smaller than 30 micrometer, and/or (B) of which at least 80 volume % has a size less than 20 micrometer, and/or (C) of which at least 80 volu

Assignees

• Nutricia Nv

Inventors

• Arakaki Cecilia
• Valk Maarten Pieter
• Moonen Raoul Charles Johan

Classifications

• A23L33/125

  containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates (indigestible substances A23L33/21) · CPC title

• A23L33/115

  Fatty acids or derivatives thereof; Fats or oils · CPC title

• A23L33/19

  Dairy proteins · CPC title

• A23P10/40

  free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added (A23P10/20, A23P10/30 take precedence) · CPC title

• A23L33/40

  Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula · CPC title