Polymers including active agents
US-2015306227-A1 · Oct 29, 2015 · US
Polymer particles
US9688788B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9688788-B2 |
| Application number | US-201414536394-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 7, 2014 |
| Priority date | Nov 8, 2013 |
| Publication date | Jun 27, 2017 |
| Grant date | Jun 27, 2017 |
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- Title
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Abstract
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Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
First claim
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We claim: 1. A method of making a spherical polymer particle comprising: reacting an aqueous based prepolymer solution including at least one derivatized polyether macromer and an initiator in an oil to form the spherical polymer particle; wherein said spherical polymer particle has a diameter less than about 1,200 μm. 2. The method of claim 1 , wherein the oil is a mineral oil. 3. The method of claim 1 , wherein the initiator is ammonium persulfate, tetramethylethylene diamine, or a combination thereof. 4. The method of claim 1 , wherein the polymer particle has a diameter between about 40 μm and about 1,200 μm. 5. The method of claim 1 , wherein the at least one derivatized polyether macromer is a derivative of poly(ethylene glycol), poly(propylene glycol), poly(tetramethylene oxide), or a combination thereof. 6. The method of claim 5 , wherein the at least one derivatized polyether macromer is poly(ethylene glycol) diacrylamide, poly(ethylene glycol) diacrylate, poly(ethylene glycol) dimethacrylate, poly(ethylene glycol) dimethacrylamide, or a combination thereof. 7. The method of claim 5 , wherein the at least one derivatized polyether macromer is poly(ethylene glycol) diacrylamide 10,000. 8. The method of claim 1 , further comprising at least one monomer. 9. The method of claim 8 , wherein the at least one monomer is glycerol monomethacrylate, amino ethyl methacrylate, 3-sulfopropyl acrylate, amino propyl methacrylamide, or a combination thereof. 10. The method of claim 8 , wherein the monomer is not n-isopropyl acrylamide.
Assignees
Inventors
Classifications
Polyvinyl alcohol {; Vinyl alcohol} · CPC title
Acrylamide; Methacrylamide · CPC title
Esters containing sulfur · CPC title
containing no aromatic rings in the alcohol moiety · CPC title
and containing two or more oxygen atoms · CPC title
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Frequently asked questions
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- What does patent US9688788B2 cover?
- Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
- Who is the assignee on this patent?
- Terumo Corp
- What technology area does this patent fall under?
- Primary CPC classification C08F22/385. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 27 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).