Tubulysin compounds, methods of making and use
US-9382289-B2 · Jul 5, 2016 · US
Tubulysin compounds, methods of making and use
US9688721B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9688721-B2 |
| Application number | US-201615171592-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 2, 2016 |
| Priority date | Feb 14, 2013 |
| Publication date | Jun 27, 2017 |
| Grant date | Jun 27, 2017 |
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- Title
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Abstract
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Tubulysin compounds of the formula (I) where R 1 , R 2 R 3a , R 3b , R 4 , R 5 , W, and n are as defined herein, are anti-mitotic agents that can be used in the treatment of cancer, especially when conjugated to a targeting moiety.
First claim
Opening claim text (preview).
What is claimed is: 1. A compound having a structure represented by formula (I-2):
Assignees
Inventors
Classifications
- C07K5/1024Primary
with the first amino acid being heterocyclic · CPC title
Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent (peptidic linkers A61K47/65) · CPC title
the drug being a protein or peptide, e.g. transferrin or bleomycin · CPC title
having 5 to 11 amino acids · CPC title
Tetrapeptides · CPC title
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- What does patent US9688721B2 cover?
- Tubulysin compounds of the formula (I) where R 1 , R 2 R 3a , R 3b , R 4 , R 5 , W, and n are as defined herein, are anti-mitotic agents that can be used in the treatment of cancer, especially when conjugated to a targeting moiety.
- Who is the assignee on this patent?
- Bristol Myers Squibb Co
- What technology area does this patent fall under?
- Primary CPC classification C07K5/1024. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 27 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).