Tubulysin compounds, methods of making and use
US-8980824-B2 · Mar 17, 2015 · US
Tubulysin compounds, methods of making and use
US9109008B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9109008-B2 |
| Application number | US-201414177498-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 11, 2014 |
| Priority date | Feb 14, 2013 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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Abstract
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Tubulysin compounds of the formula (I) where R 1 , R 2 R 3a , R 3b , R 4 , R 5 , W, and n are as defined herein, are anti-mitotic agents that can be used in the treatment of cancer, especially when conjugated to a targeting moiety.
First claim
Opening claim text (preview).
What is claimed is: 1. A compound having a structure represented by formula (I-5), (I-6), or (I-7): 2. A compound according to claim 1 , having a structure represented by formula (I-7):
Assignees
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Tetrapeptides · CPC title
the tumour determinant being from lung cancer cell · CPC title
the antibody targeting a determinant of a tumour cell · CPC title
Dipeptides · CPC title
Dipeptides · CPC title
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- What does patent US9109008B2 cover?
- Tubulysin compounds of the formula (I) where R 1 , R 2 R 3a , R 3b , R 4 , R 5 , W, and n are as defined herein, are anti-mitotic agents that can be used in the treatment of cancer, especially when conjugated to a targeting moiety.
- Who is the assignee on this patent?
- Bristol Myers Squibb Co
- What technology area does this patent fall under?
- Primary CPC classification C07K5/06139. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).