Dermatologically effective yeast extract

Patent metadata

Field	Value
Publication number	US-9655934-B2
Application number	US-201214128244-A
Country	US
Kind code	B2
Filing date	Jun 14, 2012
Priority date	Jun 29, 2011
Publication date	May 23, 2017
Grant date	May 23, 2017

Abstract

The invention relates to a method for producing a dermatologically active yeast extract, comprising the following steps: providing a preculture of the yeast cells, culturing the cells for at least fifteen minutes at a pH of 1.8-4, harvesting the cells and lysing the cells, and a yeast extract produced thereby and products comprising said yeast extract.

First claim

The invention claimed is:

1. A method of producing a dermatologically active yeast extract, said method comprising:
providing a preculture of yeast cells selected from the group consisting of Yarrowia, Saccharomyces , and Pichia yeast cells;
subjecting the preculture of yeast cells to an initial culturing step, wherein said initial culturing step is performed for at least 1 hour at a temperature of 34-39° C. and at a pH>5;
culturing the yeast cells for at least fifteen minutes and at a pH of 1.8-4;
harvesting the yeast cells; and
lysing the yeast cells, wherein said lysis provides said yeast extract.

2. The method according to claim 1 , wherein said lysing is carried out using a water-based lysis agent.

3. The method according to claim 1 , wherein said culturing step is carried out at a temperature of 34-39° C.

4. The method according to claim 1 , wherein said initial culturing step lasts 3-5 hours.

5. The method according to claim 1 , wherein said culturing step lasts 45-75 minutes.

6. The method according to claim 1 , wherein said initial culturing step and said culturing step are carried out at a temperature of 36-38° C.

7. The method according to claim 1 , wherein said culturing step is carried out at a pH of 1.9-2.2.

8. The method according to claim 1 , wherein said initial culturing step is carried out for 3-5 hours at a temperature of 36-38° C., said culturing step is carried out at a pH of 1.9-2.2, at a temperature of 36-38° C. and for 45-75 minutes and the yeast cells are yeast cells of the genus Yarrowia .

Assignees

• Schiemann Yvonne
• Farwick Mike
• Haas Thomas
• Wessel Mirja
• Evonik Degussa Gmbh

Inventors

• Schiemann Yvonne
• Farwick Mike
• Haas Thomas
• Wessel Mirja

Classifications

• A61P9/00

  Drugs for disorders of the cardiovascular system · CPC title

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61P9/10

  for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis · CPC title

• A61P3/10

  for hyperglycaemia, e.g. antidiabetics · CPC title

• A61P3/02

  Nutrients, e.g. vitamins, minerals · CPC title