Soft suture anchor

Patent metadata

Field	Value
Publication number	US-9655609-B2
Application number	US-201414328210-A
Country	US
Kind code	B2
Filing date	Jul 10, 2014
Priority date	Jul 10, 2013
Publication date	May 23, 2017
Grant date	May 23, 2017

Abstract

Compositions and materials for making soft suture anchors comprising materials that improve osteointegration have been developed. These compositions and materials comprise bioceramics, resorbable materials, and combinations thereof. A preferred embodiment comprises a soft suture anchor comprising a resorbable ceramic and a resorbable suture.

First claim

We claim:

1. A soft suture anchor comprising a suture component and an anchor component wherein the anchor component comprises fibers comprising a blend of a bioceramic and one or more resorbable polymers, wherein the bioceramic is dispersed in the fibers of the anchor, and wherein the suture component is permanent, resorbable, a hybrid of permanent and resorbable materials, monofilament, braided, single or multiple threads.

2. The soft suture anchor of claim 1 wherein the bioceramic is resorbable.

3. The soft suture anchor of claim 2 wherein the bioceramic is resorbable and selected from the group consisting of α-tricalcium phosphate (α-TCP), β-TCP, or a combination of α- and β-TCP, biphasic calcium phosphate (BCP), hydroxylapatite, calcium sulfate, calcium carbonate, or a calcium phosphate salt-based bioceramic.

4. The soft suture anchor of claim 1 wherein the the one or more resorbable polymers is selected from the group consisting of poly(orthoester), polyanhydride, poly(phosphazene), polyhydroxyalkanoate, polycarbonate, tyrosine polycarbonate, polyamide, polypeptide, poly(amino acid), polyesteramide, poly(alkylene alkylate), polyether, polyethylene glycol, polyethylene oxide, polyvinyl pyrrolidone, polyurethane, polyetherester, polyacetal, polycyanoacrylate, poly(oxyethylene)/poly(oxypropylene) copolymer, polyacetal, polyketal, polyphosphate, polyphosphoester, polyalkylene oxalate, polyalkylene succinate, poly(maleic acid), silk, recombinant silk, chitin, chitosan, polysaccharide, and polymers comprising glycolic acid, lactic acid, 1,4-dioxanone, trimethylene carbonate, 3-hydroxybutyric acid, 4-hydroxybutyrate, and β-caprolactone, including polyglycolic acid, polylactic acid, polydioxanone, polycaprolactone, copolymers of glycolic and lactic acids, polyacrylic acids, and poly(lactide-co-caprolactone).

5. The soft suture anchor of claim 4 wherein the the one or more resorbable polymers is poly-4-hydroxybutyrate or copolymer thereof.

6. The soft suture anchor of claim 1 wherein the the one or more resorbable polymers in the blend is selected from the group consisting of polymers and copolymers of ethylene and propylene, including ultra-high molecular weight polyethylene, ultra-high molecular weight polypropylene, nylon, polyesters, poly(ethylene terephthalate), poly(tetrafluoroethylene), polyurethanes, poly(ether-urethanes), poly(methylmethacrylate), polyether ether ketone, and poly(ethylene oxide).

7. The soft suture anchor of claim 1 wherein the suture component is undyed, dyed or patterned.

8. The soft suture anchor of claim 1 wherein the suture component is permanent and is made from one or more of the following: ultra-high molecular weight polyethylene, ultra-high molecular weight polypropylene, nylon, polyester, poly(ethylene terephthalate), poly(tetrafluoroethylene), polyurethane, or poly(ether-urethane).

9. The soft suture anchor of claim 1 wherein the suture component is resorbable made from polymers comprising glycolic acid, lactic acid, 1,4-dioxanone, trimethylene carbonate, 3-hydroxybutyric acid, 4-hydroxybutyric acid, ε-caprolactone, including polyglycolic acid, polylactic acid, polydioxanone, polycaprolactone, poly-4-hydroxybutyrate homopolymer or copolymers thereof.

10. The soft suture anchor of claim 1 wherein the anchor component is made by braiding, knitting, weaving, tying, injection molding, extrusion, including fiber extrusion, film extrusion, and tube extrusion, 3-D printing, molding or machining.

11. The soft suture anchor of claim 10 wherein the anchor component comprises (i) one or more slivers of film, (ii) a slotted tube, (iii) a ring and hinging struts, (iv) cone and collar, (v) braid or braids of monofilament fiber, multifilament fiber, or combinations thereof, (vi) a flat tape, (vii) a foam, (vi) a tube, sleeve, sheath, ribbon, tape or cylinder, or (vii) a slipknot including a hangman's noose.

12. The soft suture anchor of claim 1 further comprising a therapeutic, prophylactic or diagnostic agent.

13. The soft suture anchor of claim 1 further comprising a contrast agent, radiopaque marker or radioactive substance.

14. The soft suture anchor of claim 1 further comprising a bioceramic coating.

15. The soft suture anchor of claim 1 wherein the soft suture anchor has a pullout strength of at least 25 N.

16. The soft suture anchor of claim 1 wherein the soft suture anchor is configured to be used to fix soft tissue to bone and bone to bone.

17. The soft suture anchor of claim 1 wherein the soft suture anchor is configured to be used in Bankart lesion repair, SLAP lesion repair, acromion-clavicular repair, capsular shift/capsulolabral reconstruction, deltoid repair, rotator cuff tear repair, biceps tenodesis, foot and ankle medial/lateral repair and reconstruction, mid- and forefoot repair, Hallux valgus reconstruction, metatarsal ligament/tendon repair and reconstruction, Achilles tendon repair, ulnar or radial collateral ligament reconstruction, lateral epicondylitis repair, biceps tendon reattachment, knee extra-capsular repair, iliotibial band tenodesis, patellar tendon repair, VMO advancement, knee joint capsule closure, hand and wrist collateral ligament repair, scapholunate ligament reconstruction, tendon transfers in phalanx, volar plate reconstruction, acetabular labral repair, plastic and reconstructive surgery including forehead lifting, brow lifting, eyelid lifting, facelift, neck lift, breast reconstruction, breast reduction, breast augmentation, mastopexy, pelvic floor reconstruction, urethral suspension, anterior ligament repair, spinal repair, or fracture fixation.

18. A method of preparing the soft suture anchor of claim 1 comprising providing powder or pellets of polymer and bioceramic, melting and extruding a blend of the polymer and the bioceramic, extruding fibers from the blend of the polymer and the bioceramic, and forming the anchor component by braiding knitting or weaving the fibers wherein the bioceramic is dispersed in the fibers, the method further comprising combining the anchor component with a suture component, wherein the suture component is permanent resorbable, a hybrid of permanent and resorbable materials, monofilament braided, single or multiple threads.

19. A method for securing soft tissue to bone comprising forming a hole in a bone, inserting the anchor of the soft suture anchor of claim 1 into the hole, retaining the anchor in the hole, changing the shape of the anchor so that it is retained in the hole, and using the suture of the soft suture anchor to secure soft tissue to the reattachment site, or adjacent to the bone hole.

20. The soft suture anchor of claim 1 , wherein the fibers of the anchor component do not include ultrahigh molecular weight polyethylene.

Assignees

• Tepha Inc

Inventors

• Rizk Said
• Martin David P
• Bernasconi Matthew
• Williams Simon F

Classifications

• A61L31/127 Primary

  containing fillers of phosphorus-containing inorganic materials · CPC title

• A61B2017/0464

  for soft tissue · CPC title

• A61L31/128

  containing other specific inorganic fillers not covered by A61L31/126 or A61L31/127 · CPC title

• C08L67/04

  Polyesters derived from hydroxycarboxylic acids, e.g. lactones (C08L67/06 takes precedence) · CPC title

• B29C47/0038

  Operations & Transport · mapped topic