Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof
US-9226974-B2 · Jan 5, 2016 · US
US9580467B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9580467-B2 |
| Application number | US-201514939547-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 12, 2015 |
| Priority date | Aug 3, 2009 |
| Publication date | Feb 28, 2017 |
| Grant date | Feb 28, 2017 |
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Antiproliferative compounds having a structure represented by formula (II), where n, R 1 , R 2 , R 3 , R 4 , and R 5 are as defined herein, can be used to treat tumors, optionally when conjugated to a ligand such as an antibody:
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What is claimed is: 1. A compound having a structure according to formula (VI-t)
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