Medical devices with an activated coating
US-9273191-B2 · Mar 1, 2016 · US
Medical devices with an activated coating
US9511175B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9511175-B2 |
| Application number | US-201615054652-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 26, 2016 |
| Priority date | Feb 21, 2009 |
| Publication date | Dec 6, 2016 |
| Grant date | Dec 6, 2016 |
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- Title
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Abstract
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Implantable medical devices include a substrate having applied thereto a coating including a polymeric material possessing a core and at least one functional group known to have click reactivity.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of producing a medical device comprising: applying a coating composition including a natural polymer possessing a core and at least one functional group known to have click reactivity to a polymeric textile, whereby the coating composition imparts an activated surface to the textile via the functional group having click reactivity and the natural polymer is selected from the group consisting of chitosan, collagen, hyaluronic acid, polysaccharides and copolymers and combinations thereof. 2. The method according to claim 1 , wherein the functional group known to have click reactivity is selected from the group consisting in thiols, azides, alkynes and alkenes. 3. The method according to claim 2 , wherein the functional group known to have click reactivity is a thiol. 4. The method according to claim 2 , wherein the functional group known to have click reactivity is an azide. 5. The method according to claim 2 , wherein the functional group known to have click reactivity is an alkyne. 6. The method according to claim 2 , wherein the functional group known to have click reactivity is an alkene. 7. The method according to claim 1 , wherein the natural polymer comprises chitosan. 8. The method according to claim 1 , wherein the polymeric textile is a surgical mesh. 9. The method according to claim 1 , wherein the polymeric textile is a sling. 10. The method according to claim 1 , wherein applying the coating composition includes dipping, wiping, spraying, total immersion, or co-extrusion. 11. The method according to claim 1 , wherein the coating composition comprises a solution or suspension. 12. The method according to claim 1 , wherein the coating composition comprises a solvent. 13. The method according to claim 1 , further comprising adding a bioactive agent possessing a functional group having click reactivity complementary to the functional group having click reactivity of the coating composition, wherein the bioactive agent covalently bonds to the coating composition. 14. The method according to claim 13 , wherein the bioactive agent is selected from the group consisting of anti-adhesives, antimicrobials, analgesics, antipyretics, anesthetics, antiepileptics, antihistamines, anti-inflammatories, cardiovascular drugs, diagnostic agents, sympathomimetics, cholinomimetics, antimuscarinics, antispasmodics, muscle relaxants, adrenergic neuron blockers, antineoplastics, immunogenic agents, immunosuppressants, gastrointestinal drugs, diuretics, steroids, lipids, platelet activating drugs, dotting factors, chemotherapeutics and combinations thereof. 15. The method according to claim 1 , wherein the polymeric textile comprises a non-absorbable polymer. 16. The method according to claim 1 , wherein the polymeric textile comprises an absorbable polymer. 17. The method according to claim 1 , wherein the polymeric textile comprises a knit. 18. The method according to claim 1 , further comprising knitting a polymeric textile prior to applying the coating composition.
Assignees
Inventors
Classifications
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
Biologically active materials, e.g. therapeutic substances {(A61L31/047 takes precedence)} · CPC title
with natural macromolecular compounds or derivatives thereof (with natural rubber or derivatives thereof D06M15/693) · CPC title
Processes for applying liquids or other fluent materials (B05D5/00, B05D7/00 take precedence) · CPC title
- A61L31/10Primary
Macromolecular materials · CPC title
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Frequently asked questions
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- What does patent US9511175B2 cover?
- Implantable medical devices include a substrate having applied thereto a coating including a polymeric material possessing a core and at least one functional group known to have click reactivity.
- Who is the assignee on this patent?
- Sofradim Production, Covidien Lp
- What technology area does this patent fall under?
- Primary CPC classification A61L31/10. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Dec 06 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).