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Medical devices with an activated coating
US9273191B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9273191-B2 |
| Application number | US-201013202390-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 22, 2010 |
| Priority date | Feb 21, 2009 |
| Publication date | Mar 1, 2016 |
| Grant date | Mar 1, 2016 |
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- Title
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Abstract
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Implantable medical devices include a substrate having applied thereto a coating including a polymeric material possessing a core and at least one functional group known to have click reactivity.
First claim
Opening claim text (preview).
What is claimed is: 1. A medical device comprising a polymeric textile having a coating, the coating comprising a natural polymer possessing a functional group having click reactivity selected from the group consisting of thiols, azides, alkynes and alkenes, wherein the coating imparts an activated surface to the textile via the functional group having click reactivity, wherein the natural polymer is selected from the group consisting of chitosan, collagen, hyaluronic acid, polysaccharides and copolymers and combinations thereof. 2. The medical device according to claim 1 , wherein the functional group known to have click reactivity is a thiol. 3. The medical device according to claim 1 , wherein the functional group known to have click reactivity is an azide. 4. The medical device according to claim 1 , wherein the functional group known to have click reactivity is an alkyne. 5. The medical device according to claim 1 , wherein the functional group known to have click reactivity is an alkene. 6. The medical device according to claim 1 , wherein the natural polymer is chitosan. 7. The medical device of claim 1 , wherein the polymeric textile is a surgical mesh. 8. The medical device of claim 1 , wherein the polymeric textile is a sling. 9. The medical device of claim 1 , further comprising a bioactive agent possessing a functional group having click reactivity complementary to the functional group having click reactivity of the coating, wherein the bioactive agent is covalently bonded to the surface of the coated polymeric textile via the activated surface. 10. The medical device of claim 9 , wherein the bioactive agent is selected from the group consisting of anti-adhesives, antimicrobials, analgesics, antipyretics, anesthetics, antiepilutics, antihistamines, anti-intlammatories, cardiovascular drugs, diagnostic agents, synipathominietics, cholinomimetics, anti ics, antispasmodics, muscle relaxants adrenergic neuron Mockers, antineoplastics, immunogenic agents, immunosuppressants, gastrointestinal drugs, diuretics, steroids, lipids, platelet activating drugs, clotting factors chemotherapeutics and combinations thereof.
Assignees
Inventors
Classifications
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
Coating · CPC title
- A61L31/10Primary
Macromolecular materials · CPC title
with only one layer of a composition containing a polymer binder (with more layers C08J7/042) · CPC title
Coatings · CPC title
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Frequently asked questions
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- What does patent US9273191B2 cover?
- Implantable medical devices include a substrate having applied thereto a coating including a polymeric material possessing a core and at least one functional group known to have click reactivity.
- Who is the assignee on this patent?
- Ladet Sébastien, Hadba Ahmad Robert, Sofradim Production, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification A61L31/10. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Mar 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).