Method for determining a shape correction value F for laboratory liquid-analysis cuvettes

Patent metadata

Field	Value
Publication number	US-9494417-B2
Application number	US-201113978143-A
Country	US
Kind code	B2
Filing date	Dec 19, 2011
Priority date	Jan 4, 2011
Publication date	Nov 15, 2016
Grant date	Nov 15, 2016

Abstract

A method for determining a shape correction value F for a laboratory liquid-analysis cuvette comprising a cuvette body with a circular cross-section for a photometric liquid analysis includes optically measuring an inside diameter d 1 or an outside diameter d 0 of the cuvette body to obtain a measured cuvette body diameter d 1 ;d 0 . A shape correction value F is calculated from the measured cuvette body diameter d 1 ;d 0 . The shape correction value F for the cuvette body is stored.

First claim

What is claimed is:

1. A method for determining a shape correction value for a laboratory liquid-analysis cuvette comprising a cuvette body with an opening side, a bar code and a cross-section for a photometric liquid analysis of a sample in an analyzer,
the analyzer comprising:
a photometer comprising a photometer transmitter and a photometer receiver which determine a signal value by measuring along a photometric measuring path; and
an analyzer control;

the method comprising:
providing a digital camera;
providing a measuring computer;
providing a printer;
providing the laboratory liquid-analysis cuvette;
optically measuring at least one of an inside diameter and an outside diameter of the cuvette body with the digital camera by taking a picture of the opening side of the cuvette body;
determining at least one of the inside diameter and the outside diameter of the cuvette body in a plurality of rotational positions with the measuring computer based on the optical measurement;
generating an average value for at least one of the inside diameter and the outside diameter of the cuvette body with the measuring computer;
calculating a shape correction value with the measuring computer from the average value, the shape correction value being a value which correlates with a deviation of an exact length of the photometric measuring path inside the cuvette body with an ideal photometric measuring path length;
printing the shape correction value as a two-dimensional barcode for the cuvette body with the printer; and
adhering the two-dimensional barcode comprising the shape correction value to the cuvette body,
wherein, during the photometric liquid analysis of the sample,
the shape correction value is provided to the analyzer control of the analyzer, and
the analyzer control calculates an analyte measuring value from the signal value and the shape correction value.

2. The method as recited in claim 1 , wherein the analyzer further comprises a barcode reader configured to read the two dimensional barcode.

3. The method as recited in claim 1 , wherein the analyzer further comprises a cuvette turning device configured to turn the laboratory liquid-analysis cuvette.

4. The method as recited in claim 1 , wherein, after optically measuring at least one of the inside diameter and the outside diameter of the cuvette body to obtain the measured cuvette body diameter, the method further comprises:
filling the laboratory liquid-analysis cuvette with a reagent configured to react in a detectable manner with an analyte in a liquid to be analyzed; and
closing the laboratory liquid-analysis cuvette with a transport closure.

5. The method as recited in claim 1 , wherein the shape correction value is calculated from both the measured inner diameter and from the measured outer diameter.

6. The method as recited in claim 1 , wherein the cross section of the cuvette body is circular.

7. A system for measuring a shape-corrected absorbance of an analyte in a sample, the system comprising:
an analyzer comprising,
an analyzer control,
a photometer comprising a photometer transmitter and a photometer receiver configured to measure along a photometric measuring path, and
a barcode reader configured to read a two dimensional barcode;

a laboratory liquid-analysis cuvette comprising,
a cuvette body comprising a cross-section and an opening side, the laboratory liquid-analysis cuvette being configured to have a reagent react with the analyte in the sample in a detectable manner when placed therein,
a two-dimensional barcode adhered to the cuvette body, and
a shape correction value stored for the cuvette body in the two-dimensional barcode;

a digital camera configured to perform an optical measurement of at least one of an inside diameter and an outside diameter of the cuvette body by taking a picture of the opening side of the cuvette body;
a printer; and
a measuring computer configured,
to generate an average value for at least one of the inside diameter and the outside diameter of the cuvette body based on the optical measurement,
to calculate the shape correction value from the average value, the shape correction value being a value which correlates with a deviation of an exact length of the photometric measuring path inside the cuvette body with an ideal photometric measuring path length, and
to store the shape correction value as the two-dimensional barcode for the cuvette body via the printer,

wherein,
the photometer is configured to measure along the photometric measuring path so as to obtain a first absorbance of the analyte in the sample, and
the analyzer control is configured to correct the first absorbance with the shape correction value read by the barcode reader so as to determine the shape-corrected absorbance of the analyte in the sample.

8. The system as recited in claim 7 , further comprising:
a cuvette turning device configured to turn the laboratory liquid-analysis cuvette so that a plurality of optical measurements of the inside diameter or of the outside diameter of the cuvette body is performed by the digital camera,
wherein, the shape correction value is calculated based on the plurality of optical measurements.

9. The system as recited in claim 7 , wherein,
the digital camera is configured to perform an optical measurement of the inside diameter of the cuvette body to obtain a measured inside diameter, and an optical measurement of the outside diameter of the cuvette body to obtain a measured outside diameter, and
the shape correction value is calculated from both the measured inner diameter and from the measured outer diameter.

10. The system as recited in claim 7 , wherein the cross section of the cuvette body is circular.

Assignees

• Stefan Frank
• Hach Lange Gmbh

Inventors

• Stefan Frank

Classifications

• G01B11/08 Primary

  for measuring diameters · CPC title

• G01N21/5911

  of the scanning type (scanning per se G02B) · CPC title

• G01N2201/121

  Correction signals · CPC title

• B01L2300/0654

  Lenses; Optical fibres · CPC title

• B01L2200/143

  Quality control, feedback systems · CPC title