N-maleimidyl polymer derivatives

US9493609B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9493609-B2
Application numberUS-201514865362-A
CountryUS
Kind codeB2
Filing dateSep 25, 2015
Priority dateFeb 22, 2000
Publication dateNov 15, 2016
Grant dateNov 15, 2016

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a N-maleimidyl moiety without a linking group therebetween. The invention also provides two methods of preparing such linkerless N-maleimidyl polymer derivatives.

First claim

Opening claim text (preview).

That which is claimed is: 1. A multi-functional N-maleimidyl polymer derivative having the formula: wherein: X is aldehyde; and n is about 20 to about 4000.

Assignees

Inventors

Classifications

  • Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers · CPC title

  • obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin · CPC title

  • Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule · CPC title

  • Polymers modified by chemical after-treatment · CPC title

  • cyclic · CPC title

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What does patent US9493609B2 cover?
The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a N-maleimidyl moiety without a linking group therebetween. The invention also provides two methods of prepa…
Who is the assignee on this patent?
Nektar Therapeutics
What technology area does this patent fall under?
Primary CPC classification C08G65/33337. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Nov 15 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).