Protein-polymer-drug conjugates
US-2016220696-A1 · Aug 4, 2016 · US
N-maleimidyl polymer derivatives
US8992902B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8992902-B2 |
| Application number | US-201414283788-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 21, 2014 |
| Priority date | Feb 22, 2000 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a N-maleimidyl moiety without a linking group therebetween. The invention also provides two methods of preparing such linkerless N-maleimidyl polymer derivatives.
First claim
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That which is claimed is: 1. A multi-functional N-maleimidyl polymer derivative having the formula: wherein: X is amine; and n is about 20 to about 4000.
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Classifications
Human Necessities · mapped topic
Human Necessities · mapped topic
- C08G65/33396Primary
Chemistry & Metallurgy · mapped topic
- C08G65/48Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US8992902B2 cover?
- The invention is directed to multi-functional N-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a N-maleimidyl moiety without a linking group therebetween. The invention also provides two methods of prepa…
- Who is the assignee on this patent?
- Nektar Therapeutics
- What technology area does this patent fall under?
- Primary CPC classification C08G65/33396. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).