Conformations of divergent peptides with mineral binding affinity

US9415114B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9415114-B2
Application numberUS-201514805588-A
CountryUS
Kind codeB2
Filing dateJul 22, 2015
Priority dateApr 21, 2011
Publication dateAug 16, 2016
Grant dateAug 16, 2016

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

A series of peptides with divergent confirmations including structures of formula (1A), (1B), (2) and (3) are provided. In the formula, wherein U, G, A, B, R1, R2 and T are as defined in the specification. The divergent peptides disclosed in the present invention are characterized in a mineral binding affinity function.

First claim

Opening claim text (preview).

What is claimed is: 1. A pharmaceutical composition, comprising a pharmaceutically acceptable carrier and an effective amount of a compound having a formula 3: wherein R1 is -(Asp-)K, R2 is one selected from a group consisting of a polyamindoamine dendrimer (PAMAM), a polyester type dendrimer, a polyglycerol dendrimer, a triazine based dendrimer, a poly(propyleneimine)dendrimer and a Newkome-type dendrimer, where 64≧T≧1, 20≧K≧1, where T and K are natural numbers, Asp represents an aspartic acid, and Gly represents a glycine. 2. A divergent compound, comprising a structure having a formula 3: wherein R1 is -(Asp-)K, R2 is one selected from a group consisting of a polyamindoamine dendrimer (PAMAM), a polyester type dendrimer, a polyglycerol dendrimer, a triazine based dendrimer, a poly(propyleneimine)dendrimer and a Newkome-type dendrimer, where 64≧T≧1, 20≧K≧1, T and K are natural numbers, Asp represents an aspartic acid, and Gly represents a glycine. 3. A divergent compound as claimed in claim 2 , wherein R2 is a polyamindoamine dendrimer (PAMAM).

Assignees

Inventors

Classifications

  • C07K5/0815Primary

    with the first amino acid being basic · CPC title

  • Polymers modified by chemical after-treatment · CPC title

  • C08G73/028Primary

    Polyamidoamines · CPC title

  • Human Necessities · mapped topic

  • Tripeptides · CPC title

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What does patent US9415114B2 cover?
A series of peptides with divergent confirmations including structures of formula (1A), (1B), (2) and (3) are provided. In the formula, wherein U, G, A, B, R1, R2 and T are as defined in the specification. The divergent peptides disclosed in the present invention are characterized in a mineral binding affinity function.
Who is the assignee on this patent?
Univ Kaohsiung Medical
What technology area does this patent fall under?
Primary CPC classification C07K5/0815. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 16 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).