Sterile filling system for on-line particle adding

Patent metadata

Field	Value
Publication number	US-9346025-B2
Application number	US-201113580854-A
Country	US
Kind code	B2
Filing date	Feb 23, 2011
Priority date	Feb 23, 2010
Publication date	May 24, 2016
Grant date	May 24, 2016

Abstract

The present invention relates to a sterile filling system, and specifically relates to a sterile filling system for on-line particle adding comprising a filling system, characterized in that it further comprises a system for on-line particle adding. The filling system comprises a first AP valve bank and an injection pipe, the first AP valve bank and the injection pipe being in connection with each other; and the system for on-line particle adding comprises a second AP valve bank, the second AP valve bank being in connection with the injection pipe. The present invention can achieve the object of addition of solid particles during the production of liquid product, and ensure that the finished product will meet the requirement for sterility.

First claim

The invention claimed is:

1. A sterile filling system for on-line particle adding comprising:
a filling system;
a system for on-line particle adding;
the filling system comprising a first AP valve bank and an injection pipe connected to each other;
the system for on-line particle adding comprising a second AP valve bank;
the second AP valve bank being connected to the injection pipe through a communicating pipe and a mixing nozzle;
the second AP valve bank being connected to the first AP valve bank through the mixing nozzle so that a first product being conveyed along the injection pipe from the first AP valve bank is mixed with a second product which has been ejected from the mixing nozzle downstream of the mixing nozzle, the second product being from the second AP valve bank;
the mixing nozzle being disposed on the communicating pipe; and
wherein the first AP valve bank and the second AP valve bank are connected to the injection pipe through the mixing nozzle.

2. The sterile filling system for on-line particle adding according to claim 1 , wherein the second AP valve bank is connected to the injection pipe through a second flow control valve.

3. The sterile filling system for on-line particle adding according to claim 2 , wherein the second flow control valve is connected to the injection pipe through the communicating pipe, on which pipe is disposed a flow transducer and a dosing valve.

4. The sterile filling system for on-line particle adding according to claim 1 , wherein the first AP valve bank is connected to the injection pipe through a first flow control valve.

5. The sterile filling system for on-line particle adding according to claim 1 , further comprising an on-line cleaning system.

6. The sterile filling system for on-line particle adding according to claim 5 , wherein the cleaning system comprises an outer cleaning station and a plurality of reversible pipes, the reversible pipes being detachably connected to channels of the filling system and being configured to connect to the outer cleaning station, the filling system, and the system for on-line particle adding in a reversible manner to form series connected cleaning pipeline.

7. The sterile filling system for on-line particle adding according to claim 6 , wherein the injection pipe is connected to the outer cleaning station through a filling pipe.

8. The sterile filling system for on-line particle adding according to claim 1 , wherein the communicating pipe is a second communicating pipe, the second AP valve bank is connected to the second communicating pipe, and the first AP valve bank is connected to a first communicating pipe, the second communicating pipe meeting the first communicating pipe at a junction, and the injection pipe bending at a curved part.

9. The sterile filling system for on-line particle adding according to claim 8 , wherein the mixing nozzle is disposed near the junction and a distance of the end of the mixing nozzle near the junction from the curved part is between 1 m and 3 m.

10. The sterile filling system for on-line particle adding according to claim 9 , wherein the distance of the end of the mixing nozzle near the junction from the curved part is between 2 m and 2.5 m.

11. The sterile filling system for on-line particle adding according to claim 9 , wherein the distance of the end of the mixing nozzle near the junction from the curved part is between 1.5 m and 2 m.

12. The sterile filling system for on-line particle adding according to claim 9 , wherein the mixing nozzle possesses a plurality of through-holes which are connected to the second AP valve bank and the injection pipe and further connected to the second AP valve bank and the first AP valve bank.

13. The sterile filling system for on-line particle adding according to claim 12 , wherein the shape of mixing nozzle is cylinder-, cone- or circular truncated cone-shaped.

14. The sterile filling system for on-line particle adding according to claim 13 , wherein the mixing nozzle has a length along the direction of the through-holes ranging from 10 mm to 60 mm.

15. The sterile filling system for on-line particle adding according to claim 14 , wherein the amount of the through-holes in the mixing nozzle ranges from 16 to 24.

16. The sterile filling system for on-line particle adding according to claim 14 , wherein the mixing nozzle is configured into two segments which consist of a first segment and a second segment, each of which having different radial size, and the first segment being connected to the second segment, thereby the whole mixing nozzle having a ladder shape.

17. The sterile filling system for on-line particle adding according to claim 16 , wherein the first segment and the second segment are configured to have the through-holes with an amount ranging from 8 to 16.

18. The sterile filling system for on-line particle adding according to claim 17 , wherein the first segment and the second segment have a length along the direction of the through-holes respectively ranging from 10 mm to 50 mm.

19. The sterile filling system for on-line particle adding according to claim 18 , wherein the length along the direction of the through-holes of the first segment and the second segment are respectively one selected from the group consisting of 15 mm/20 mm, 20 mm/20 mm and 30 mm/30 mm.

20. The sterile filling system for on-line particle adding according to claim 16 , wherein the shape of each segment of the mixing nozzle is cylinder- or corrugated pipe-shaped.

21. The sterile filling system for on-line particle adding according to claim 12 , wherein the mixing nozzle is configured into three segments which consist of a third segment, a fourth segment and a fifth segment, each of which having different radial size, and the segments from to being connected in turn, thereby the whole mixing nozzle having a ladder shape.

22. The sterile filling system for on-line particle adding according to claim 21 , wherein the third segment, the fourth segment and the fifth segment are configured to have the through-holes with an amount ranging from 16 to 22.

23. The sterile filling system for on-line particle adding according to claim 22 , wherein the third segment, the fourth segment and the fifth segment have a length along the direction of the through-holes respectively ranging from 10 mm to 50 mm.

24. The sterile filling system for on-line particle adding according to claim 23 , wherein the length along the direction of the through-holes of the third segment, the fourth segment and the fifth segment are respectively one selected from the group consisting of 15 mm/15 mm/20 mm, 15 mm/20 mm/20 mm and 20 mm/20 mm/20 mm.

25. The sterile filling system for on-line particle adding according to claim 12 , wherein the mixing nozzle is configured into four segments which consist of a sixth segment, a seventh segment, an eighth segment and a ninth segment, each of which having different radial size, and the sixth, seventh, eighth and ninth segments being connected in turn, thereby the whole mixing nozzle having a ladder shape.

26. The sterile filling system for on-line particle adding according to claim 25 , wherein the sixth, seventh, eighth and ninth segments are configured to have the through-holes with an amount ranging from 16 to 22.

27. The sterile filling system for on-line particle adding according to claim 26 , wherein the mixing nozzle has a total

Assignees

• Liu Aiyuan
• Zhang Jian
• Sun Peng
• Liu Jun
• Tetra Laval Holdings & Finance

Inventors

• Liu Aiyuan
• Zhang Jian
• Sun Peng
• Liu Jun

Classifications

• B65B55/18 Primary

  by liquids or gases (B65B55/14 takes precedence) · CPC title

• B01F5/20

  Operations & Transport · mapped topic

• B01F3/0865 Primary

  Operations & Transport · mapped topic

• Y10T137/87652

  With means to promote mixing or combining of plural fluids · CPC title

• B01F2215/0431

  Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof · CPC title