Compositions and Methods for the Prevention and Treatment of Osteolysis and Osteoporosis
US-2015352131-A1 · Dec 10, 2015 · US
US9340561B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9340561-B2 |
| Application number | US-201214345002-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 28, 2012 |
| Priority date | Sep 16, 2011 |
| Publication date | May 17, 2016 |
| Grant date | May 17, 2016 |
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There is provided a novel organic silicon compound that can be used for a silane coupling agent. An organic silicon compound of Formula (1): (where A − is Formula (2) or Formula (3): E is Formula (4) or Formula (5): R 1 and R 2 are each independently a C 1-5 alkyl group, R 3 is a hydrogen atom or a methyl group, R 4 and R 5 are each independently a C 1-5 alkyl group, m, n, and p are each independently an integer of 1 to 5, and q is an integer of 1 to 3).
Opening claim text (preview).
The invention claimed is: 1. An organic silicon compound of Formula (1): where A − is Formula (2) or Formula (3): E is Formula (4) or Formula (5): a carbonyl group in each of Formula (4) and Formula (5) is bonded to a carbon atom to which R 3 is bonded, R 1 and R 2 are each independently a C 1-5 alkyl group, R 3 is a hydrogen atom or a methyl group, R 4 and R 5 are each independently a C 1-5 alkyl group, m, n, and p are each independently an integer of 1 to 5, and q is an integer of 1 to 3. 2. A silane coupling agent comprising: the organic silicon compound as claimed in claim 1 ; a polar organic solvent; and water. 3. The silane coupling agent according to claim 2 , further comprising an organic acid. 4. An adherence inhibitor for a biological substance or a cell, comprising the silane coupling agent as claimed in claim 2 . 5. The adherence inhibitor according to claim 4 , wherein the cell is a platelet. 6. A method for immobilizing a silane coupling agent, the method comprising the steps of: applying the silane coupling agent according to claim 2 onto a substrate and baking the silane coupling agent; washing the substrate with a polar solvent; and drying the substrate. 7. A method for immobilizing a silane coupling agent, the method comprising the steps of: immersing a substrate in the silane coupling agent according to claim 2 ; washing the substrate with a polar solvent; and drying the substrate. 8. An adherence inhibitor for a biological substance or a cell, comprising the silane coupling agent as claimed in claim 3 . 9. The adherence inhibitor according to claim 8 , wherein the cell is a platelet. 10. A method for immobilizing a silane coupling agent, the method comprising the steps of: applying the silane coupling agent according to claim 3 onto a substrate and baking the silane coupling agent; washing the substrate with a polar solvent; and drying the substrate. 11. A method for immobilizing a silane coupling agent, the method comprising the steps of: immersing a substrate in the silane coupling agent according to claim 3 ; washing the substrate with a polar solvent; and drying the substrate.
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Biologically active materials, e.g. therapeutic substances {(A61L27/227 takes precedence)} · CPC title
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