Beta-glucosidase variants having improved activity, and uses thereof

US9309538B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9309538-B2
Application numberUS-200913063362-A
CountryUS
Kind codeB2
Filing dateSep 10, 2009
Priority dateSep 12, 2008
Publication dateApr 12, 2016
Grant dateApr 12, 2016

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  2. Abstract

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Abstract

Official abstract text for this publication.

The present invention relates to the expression and optimization of enzymes involved in lignocellulosic biomass decomposition. The present invention relates more particularly to beta-glucosidase variants comprising at least one modification among the amino acids located at positions 225, 238, 240 and 241, according to the numbering in SEQ ID No. 2 of Trichoderma reesei beta-glucosidase, and also relates to the use of said variants having improved effectiveness in methods for cellulose decomposition and biofuel production.

First claim

Opening claim text (preview).

The invention claimed is: 1. An isolated or purified modified polypeptide comprising an amino acid sequence in which at least one amino acid is modified compared with the amino acid sequence SEQ ID No. 2, said modified amino acid being chosen from positions 225, 238, 240 and 241 of the amino acid sequence SEQ ID No. 2, wherein said modified polypeptide has the amino acid sequence SEQ ID No. 10; or at least 85% identity with said amino acid sequences SEQ ID No. 2 or SEQ ID NO. 10, a…

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  • Cross-Sectional Technologies · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • Cross-Sectional Technologies · mapped topic

  • Chemistry & Metallurgy · mapped topic

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What does patent US9309538B2 cover?
The present invention relates to the expression and optimization of enzymes involved in lignocellulosic biomass decomposition. The present invention relates more particularly to beta-glucosidase variants comprising at least one modification among the amino acids located at positions 225, 238, 240 and 241, according to the numbering in SEQ ID No. 2 of Trichoderma reesei beta-glucosidase, and a…
Who is the assignee on this patent?
Lopes-Ferreira Nicolas, Margeot Antoine, Mathis Hugues, and 3 more
What technology area does this patent fall under?
Primary CPC classification C12P7/04. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Apr 12 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).