Asgpr-binding compounds for the degradation of extracellular proteins
US-2024424108-A1 · Dec 26, 2024 · US
US9290530B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9290530-B2 |
| Application number | US-201414160451-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 21, 2014 |
| Priority date | Jul 21, 2011 |
| Publication date | Mar 22, 2016 |
| Grant date | Mar 22, 2016 |
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The present invention provides a one-pot multi-enzyme method for preparing UDP-sugars from simple sugar starting materials. The invention also provides a one-pot multi-enzyme method for preparing oligosaccharides from simple sugar starting materials.
Opening claim text (preview).
What is claimed is: 1. A sialylated oligosaccharide selected from the group consisting of: Neu5Acα2-3(Neu5Acα2-6)Galβ1-4Glc; Neu5Acα2-3(Neu5Acα2-6)Galβ1-3GalNAc; Neu5Acα2-3(Neu5Acα2-6)Galβ1-3GlcNAc; and Neu5Acα2-6Galβ1-3GlcNAcβ1-3(Neu5Acα2-6)Galβ1-4Glc. 2. A sialylated oligosaccharide which is Neu5Acα2-6Galβ1-4GlcNAcβ1-3(Neu5Acα2-6)Galβ1-4Glc. 3. A method for treating necrotizing enterocolitis (NEC), the method comprising administering to a subject in need thereof a sialylated oligosaccharide according to claim 1 . 4. A method for treating necrotizing enterocolitis (NEC), the method comprising administering to a subject in need thereof the sialylated oligosaccharide according to claim 2 .
Processes for the preparation of sugar derivatives · CPC title
Preparation of nitrogen-containing carbohydrates · CPC title
Preparation of compounds containing saccharide radicals (ketoaldonic acids C12P7/58) · CPC title
Disaccharides · CPC title
Deoxysugars; Unsaturated sugars (1,2-dideoxy-1-enoses C07D); Osones · CPC title
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