Glycodendrimers of polypropyletherimine

US9453040B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9453040-B2
Application numberUS-201113818580-A
CountryUS
Kind codeB2
Filing dateAug 22, 2011
Priority dateAug 24, 2010
Publication dateSep 27, 2016
Grant dateSep 27, 2016

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Abstract

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A glycodendrimer comprising: a) a non-toxic dendrimer polypropyletherimine core supporting on average in the range of 9 to 64 terminal carboxylic acid groups, and b) conjugated to said core in the range of 2 to 8 amino sugars or a sulphate amino sugar selected from the group consisting of glucosamine, N-acetyl glucosamine, mannosamine, N-acetylmannosamine, galactosamine, a sulphate of any one of the same and a combination thereof, wherein each sugar is linked directly through a zero length amide bond with a residue of a terminal carboxylic acid group. The invention also extends to defined populations comprising said glycodendrimer molecules, pharmaceutical compositions comprising said molecules or populations, process for preparing the molecules and formulations, and therapeutic uses of the molecules, populations and compositions.

First claim

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The invention claimed is: 1. A glycodendrimer comprising: a) a non-toxic generation 3 dendrimer polypropyletherimine core supporting 16 terminal carboxylic acid groups, wherein the dendrimer polypropyletherimine core has a central atom which is oxygen, and b) conjugated to said core 2, 3, 4 or 5 glucosamine molecures, wherein each glucosamine molecule is linked directly through a zero length amide bond with a residue of a terminal carboxylic acid group.…

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What does patent US9453040B2 cover?
A glycodendrimer comprising: a) a non-toxic dendrimer polypropyletherimine core supporting on average in the range of 9 to 64 terminal carboxylic acid groups, and b) conjugated to said core in the range of 2 to 8 amino sugars or a sulphate amino sugar selected from the group consisting of glucosamine, N-acetyl glucosamine, mannosamine, N-acetylmannosamine, galactosamine, a sulphate of any one o…
Who is the assignee on this patent?
Shaunak Sunil, Teo Ian Alfred, Imp Innovations Ltd
What technology area does this patent fall under?
Primary CPC classification C07H15/26. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).