Nutritional composition containing oligosaccharide mixture

Patent metadata

Field	Value
Publication number	US-9247764-B2
Application number	US-201414499546-A
Country	US
Kind code	B2
Filing date	Sep 29, 2014
Priority date	Jul 8, 2008
Publication date	Feb 2, 2016
Grant date	Feb 2, 2016

Abstract

A nutritional composition for administration to an infant which composition comprises, on a dry matter basis, from 2.5 to 15.0 wt % of an oligosaccharide mixture consisting of N-acetylated oligosaccharide(s), galacto-oligosaccharide(s) and sialylated oligosaccharide(s) with the proviso that the composition comprises at least 0.02 wt % of an N-acetylated oligosaccharide, at least 2.0 wt % of a galacto-oligosaccharide and at least 0.04 wt % of a sialylated oligosaccharide and that the N-acetylated oligosaccharide(s) comprise 0.5 to 4.0% of the oligosaccharide mixture, the galacto-oligosaccharide(s) comprise 92.0 to 98.5% of the oligosaccharide mixture and the sialylated oligosaccharide(s) comprise 1.0 to 4.0% of the oligosaccharide mixture. The composition is useful for administration to an infant in the first six months of life to reduce the risk of obesity later in life.

First claim

The invention is claimed as follows:

1. A method for reducing the risk of obesity later in life to an infant, the method comprising administering a nutritional composition comprising therapeutically effective amounts of an N-acetylated oligosaccharide, a galacto-oligosaccharide and a sialylated oligosaccharide to an infant in the first six months of life.

2. The method of claim 1 , wherein the N-acetylated oligosaccharide is selected from the group consisting of GalNAcα1,3Galβ1,4Glc; Galβ1,6GalNAcα1,3Galβ1,4Glc and a mixture thereof.

3. The method of claim 1 , wherein the galacto-oligosaccharide is selected from the group consisting of Galβ1,6Gal; Galβ1,6Galβ1,4Glc; Galβ1,6Galβ1,6Glc; Galβ1,3Galβ1,3Glc; Galβ1,3Galβ1,4Glc; Galβ1,6Galβ1,6Galβ1,4Glc; Galβ1,6Galβ1,3Galβ1,4Glc; Galβ1,3Galβ1,6Galβ1,4Glc; Galβ1,3Galβ1,3Galβ1,4Glc; Galβ1,4Galβ1,4Glc; and Galβ1,4Galβ1,4Galβ1,4Glc and mixtures thereof.

4. The method of claim 1 , wherein the sialylated oligosaccharide is selected from the group consisting of NeuAcα2,3Galβ1,4Glc, NeuAcα2,6Galβ1,4Glc and a mixture thereof.

Assignees

• Nestec Sa

Inventors

• Fichot Marie-Claire
• Sprenger Norbert
• Martin Francois-Pierre
• Kochhar Sunil
• Rezzi Serge

Classifications

• A61P3/04

  Anorexiants; Antiobesity agents · CPC title

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A23L33/125 Primary

  containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates (indigestible substances A23L33/21) · CPC title

• A61K35/744

  Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs · CPC title

• A23L5/00

  Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor · CPC title