Material self-assembly method and selective adhesion method based on molecular recognition

Patent metadata

Field	Value
Publication number	US-9150762-B2
Application number	US-201113822918-A
Country	US
Kind code	B2
Filing date	Sep 8, 2011
Priority date	Sep 14, 2010
Publication date	Oct 6, 2015
Grant date	Oct 6, 2015

Abstract

The present invention provides a selective adhesion method and a self-assembly method for macroscale materials based on molecular recognition. One or more host bodies formed from a macromolecule having one or more host groups on the side chains, and one or more guest bodies formed from a macromolecule having one or more guest groups on the side chains are vibrated in a solvent to selectively form an assembly.

First claim

The invention claimed is:

1. An assembly comprising one or more host bodies formed from a macromolecule having one or more host groups in the side chains, and one or more guest bodies formed from a macromolecule having one or more guest groups in the side chains, wherein the one or more host bodies and the one or more guest bodies are in contact with each other and form the assembly, wherein the one or more host bodies are a gel of a crosslinked polymer having repeating units represented by the following general formulae (1) and (2), and the one or more guest bodies are a gel of a crosslinked polymer having repeating units represented by the following general formulae (1) and (3):

wherein X represents a hydroxyl group, C(O)NH 2 , or C(O)OH, and n is 1 to 200,000,

wherein CD represents α-cyclodextrin, β-cyclodextrin, or γ-cyclodextrin, and m is 1 to 200,000,

wherein A represents O or NH, R represents an optionally-substituted alkyl group, or an optionally-substituted aryl group, and l is 1 to 200,000,
the host groups corresponding to the group CD in general formula (2), and the guest groups corresponding to the group R in general formula (3).

2. An assembly according to claim 1 , wherein the association constant between the one or more host bodies and the one or more guest bodies is 50 or more.

3. An assembly according to claim 1 , wherein the one or more host bodies are a copolymer of acrylamide and an acrylamide that has cyclodextrin on the side chain.

4. An assembly according to claim 1 , wherein the one or more guest bodies are a copolymer of acrylamide and an acryl compound selected from the group consisting of an alkyl ester of acrylic acid, an aryl ester of acrylic acid, and an acrylamide having a cycloalkyl group on the side chain.

5. A method for causing one or more host bodies formed from a macromolecule having one or more host groups on the side chains, and one or more guest bodies formed from a macromolecule having one or more guest groups on the side chains to selectively adhere to each other through contact in an aqueous solvent, the method comprising the step of contacting the macromolecule having one or more host groups on the side chains with the macromolecule having one or more guest groups on the side chain, wherein the one or more host bodies are a gel of a crosslinked polymer having repeating units represented by the following general formulae (1) and (2), and the one or more guest bodies are a gel of a crosslinked polymer having repeating units represented by the following general formulae (1) and (3):

wherein X represents a hydroxyl group, C(O)NH 2 , or C( 0 )OH, and n is 1 to 200,000,

wherein CD represents α-cyclodextrin, β-cyclodextrin, or γ-cyclodextrin, and m is 1 to 200,000,

wherein A represents O or NH, R represents an optionally-substituted alkyl group, or an optionally-substituted aryl group, and l is 1 to 200,000,
the host groups corresponding to the group CD in general formula (2), and the guest groups corresponding to the group R in general formula (3).

6. An assembly according to claim 1 , wherein the one or more host bodies are a gel of a crosslinked polymer having repeating units represented by the following general formulae (1), (2) and (3), and the one or more guest bodies are a gel of a crosslinked polymer having repeating units represented by the following general formulae (1), (2) and (3):

wherein X represents a hydroxyl group, C(O)NH 2 , or C(O)OH, and n is 1 to 200,000,

wherein CD represents α-cyclodextrin, β-cyclodextrin, or γ-cyclodextrin, and m is 1 to 200,000,

wherein A represents 0 or NH, R represents an optionally-substituted alkyl group, or an optionally-substituted aryl group, and l is 1 to 200,000,
the host groups corresponding to the group CD in general formula (2), and the guest groups corresponding to the group R in general formula (3).

7. A method for causing one or more host bodies formed from a macromolecule having one or more host groups on the side chains, and one or more guest bodies formed from a macromolecule having one or more guest groups on the side chains to selectively adhere to each other through contact in an aqueous solvent, the method comprising the step of contacting the macromolecule having one or more host groups on the side chains with the macromolecule having one or more guest groups on the side chain, wherein the one or more host bodies are a gel of a crosslinked polymer having repeating units represented by the following general formulae (1), (2) and(3), and the one or more guest bodies are a gel of a crosslinked polymer having repeating units represented by the following general formulae (1), (2) and (3):

wherein X represents a hydroxyl group, C(O)NH 2 , or C(O)OH, and n is 1 to 200,000,

wherein CD represents α-cyclodextrin, β-cyclodextrin, or γ-cyclodextrin, and m is 1 to 200,000,

wherein A represents O or NH, R represents an optionally-substituted alkyl group, or an optionally-substituted aryl group, and l is 1 to 200,000,
the host groups corresponding to the group CD in general formula (2), and the guest groups corresponding to the group R in general formula (3).

8. A method according to claim 7 , wherein the contact between the one or more host bodies and the one or more guest bodies is re-contact made after the assembly is cut.

Assignees

• Harada Akira
• Kobayashi Ryosuke
• Yamaguchi Hiroyasu
• Hashidzume Akihito
• Takashima Yoshinori
• Univ Osaka

Inventors

• Harada Akira
• Kobayashi Ryosuke
• Yamaguchi Hiroyasu
• Hashidzume Akihito
• Takashima Yoshinori

Classifications

• C08G83/008

  Supramolecular polymers · CPC title

• C08F220/54

  Amides {, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide} · CPC title

• C09J133/26

  Homopolymers or copolymers of acrylamide or methacrylamide · CPC title

• C09J105/16 Primary

  Cyclodextrin; Derivatives thereof · CPC title

• C08L33/26 Primary

  Homopolymers or copolymers of acrylamide or methacrylamide · CPC title