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Method for site-specific polyvalent display on polymers
US9107959B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9107959-B2 |
| Application number | US-201314016392-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 3, 2013 |
| Priority date | Mar 3, 2006 |
| Publication date | Aug 18, 2015 |
| Grant date | Aug 18, 2015 |
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Abstract
Official abstract text for this publication.
The present invention relates to novel complex peptidomimetic products comprising multiple homogeneous or heterogeneous pendant groups that are site-specifically positioned along a linear oligomer or polymer scaffold and methods of making thereof. More specifically, the invention relates to N-substituted glycine peptoid oligomers or peptoids and their use as substrates for azide-alkyne[3+2]-cycloaddition conjugation reactions and subsequent additional rounds of oligomerization and cycloaddition. The methods of the invention may also be used to generate peptoid-peptide hybrid or peptide products comprising multiple homogeneous or heterogeneous pendant groups, which are positioned precisely along the linear oligomer or polymer scaffold.
First claim
Opening claim text (preview).
What is claimed is: 1. A polyvalent linear peptoid comprising a plurality of heterogeneous backbone-attached pendant groups, wherein each of the heterogeneous backbone-attached pendant groups is attached to the backbone of the linear peptoid via a triazole linkage group. 2. The polyvalent linear peptoid of claim 1 , wherein the peptoid comprises between 2-1,000 monomers. 3. The polyvalent linear peptoid of claim 1 , wherein the peptoid comp…
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Classifications
- A61K47/641Primary
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
- A61K47/48315Primary
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US9107959B2 cover?
- The present invention relates to novel complex peptidomimetic products comprising multiple homogeneous or heterogeneous pendant groups that are site-specifically positioned along a linear oligomer or polymer scaffold and methods of making thereof. More specifically, the invention relates to N-substituted glycine peptoid oligomers or peptoids and their use as substrates for azide-alkyne[3+2]-cyc…
- Who is the assignee on this patent?
- Kirshenbaum Kent, Holub Justin M, Univ New York
- What technology area does this patent fall under?
- Primary CPC classification A61K47/641. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Aug 18 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).