Polypeptide applied to inhibition of intracellular lipid accumulation and synthesis method thereof
US-2024366713-A1 · Nov 7, 2024 · US
Proteas stabilized antibacterial peptides for S. aureus
US9757472B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9757472-B2 |
| Application number | US-201514808984-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 24, 2015 |
| Priority date | Jul 28, 2014 |
| Publication date | Sep 12, 2017 |
| Grant date | Sep 12, 2017 |
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Abstract
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Improved peptide compositions and synbody compositions are disclosed that show improved stability and antibiotic activity. The new antibacterial peptides for S. aureus have particular D-amino acid substitutions in order to increase protease stability while also preserving marked antibiotic activity. Thus, compositions and methods for treating infections related to S. aureus also are disclosed.
First claim
Opening claim text (preview).
What is claimed is: 1. A bactericidal composition comprising a peptide scaffold ScO: conjugated to at least one other peptide having at least one D-amino acid. 2. The composition of claim 1 , wherein said composition comprises synbody Ly-Ly-ScO:…
Assignees
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Classifications
- A61K38/16Primary
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
- A61K47/48246Primary
Human Necessities · mapped topic
- A61K47/641Primary
Human Necessities · mapped topic
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US9757472B2 cover?
- Improved peptide compositions and synbody compositions are disclosed that show improved stability and antibiotic activity. The new antibacterial peptides for S. aureus have particular D-amino acid substitutions in order to increase protease stability while also preserving marked antibiotic activity. Thus, compositions and methods for treating infections related to S. aureus also are disclosed.
- Who is the assignee on this patent?
- Diehnelt Chris, Johnston Stephen, Univ Arizona State
- What technology area does this patent fall under?
- Primary CPC classification A61K38/16. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Sep 12 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).