Variant CBH2 cellulases and related polynucleotides

US9102927B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9102927-B2
Application numberUS-201414311914-A
CountryUS
Kind codeB2
Filing dateJun 23, 2014
Priority dateSep 4, 2009
Publication dateAug 11, 2015
Grant dateAug 11, 2015

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Abstract

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The invention provides variants of a Streptomyces sp. CBH2 that have improved properties compared to the wild type enzyme and methods of using the variants in the hydrolysis of substrates comprising cellulose.

First claim

Opening claim text (preview).

We claim: 1. An isolated Streptomyces sp. cellobiohydrolase II (CBH2) polypeptide variant comprising: (a) an amino acid sequence that is at least 90%, identical to wild type Streptomyces sp CBH2 (SEQ ID NO:4) and having the substitution at position P234A or P234S, wherein amino acid position is determined by optimal alignment with SEQ ID NO:4. 2. The isolated CBH2 polypeptide variant according to claim 1 , wherein the variant amino acid sequence is at le…

Assignees

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Classifications

  • C12N9/2408Primary

    Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • Cross-Sectional Technologies · mapped topic

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What does patent US9102927B2 cover?
The invention provides variants of a Streptomyces sp. CBH2 that have improved properties compared to the wild type enzyme and methods of using the variants in the hydrolysis of substrates comprising cellulose.
Who is the assignee on this patent?
Codexis Inc
What technology area does this patent fall under?
Primary CPC classification C12N9/2408. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).