Methods for the stereoselective preparation of apiose derivatives from allylic alcohol compounds and allene compounds using catalytic asymmetric synthesis
US-2017369519-A1 · Dec 28, 2017 · US
Trioxacarcins and uses thereof
US9102697B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9102697-B2 |
| Application number | US-201113636263-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 22, 2011 |
| Priority date | Mar 22, 2010 |
| Publication date | Aug 11, 2015 |
| Grant date | Aug 11, 2015 |
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Abstract
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The present invention relates to trioxacarcin compounds of the formula: (I) or pharmaceutically acceptable forms thereof; wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , and R 9 are as defined herein. The present invention also provides processes for preparing such compounds and intermediates thereto; pharmaceutical compositions comprising such compounds; and methods of use and treatment.
First claim
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What is claimed is: 1. A compound of the Formula (I): or a pharmaceutically acceptable form thereof; wherein: R 1 is hydrogen or ═O; each instance of R 2 and R 3 is hydrogen; R 4 is hydrogen; halogen; cyclic or acyclic, substituted or unsubstituted, branched or unbranched aliphatic; cyclic or acyclic, substituted or unsubstituted, branched or unbranched h…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9102697B2 cover?
- The present invention relates to trioxacarcin compounds of the formula: (I) or pharmaceutically acceptable forms thereof; wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , and R 9 are as defined herein. The present invention also provides processes for preparing such compounds and intermediates thereto; pharmaceutical compositions comprising such compounds; and methods of use and treatment.
- Who is the assignee on this patent?
- Myers Andrew G, Hill Nicholas E, Svenda Jakub, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification C07H17/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 11 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).