Engineered microorganism producing homo-succinic acid and method for preparing succinic acid using the same
US-9217138-B2 · Dec 22, 2015 · US
Dicarboxylic acid production by fermentation at low pH
US9012187B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9012187-B2 |
| Application number | US-200913003217-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 20, 2009 |
| Priority date | Jul 8, 2008 |
| Publication date | Apr 21, 2015 |
| Grant date | Apr 21, 2015 |
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Abstract
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The present invention relates to a process for the production of a dicarboxylic acid. The process comprises fermenting a yeast in the presence of a carbohydrate-containing substrate and low amounts of oxygen at a pH value at which at least 50% of the dicarboxylic acid is in the acid form. The process of the present invention allows for high yields of the dicarboxylic acid product and is more cost-effective than existing processes in which the salt is produced which during recovery has to be converted to the acid. It also leads to a simpler and more convenient downstream processing.
First claim
Opening claim text (preview).
The invention claimed is: 1. A process for the preparation of succinic acid, comprising: fermenting a yeast in the presence of a carbohydrate-containing substrate and low amounts of oxygen at a pH value which is below the lowest pKa of the succinic acid, wherein the oxygen is supplied at a specific oxygen uptake rate ranging from 8 to 0.2 mmol oxygen/g biomass dry weight/hour, and wherein, in an acid production phase, said process produces more than 10 g/L succinic acid during cult…
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- C12P7/46Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9012187B2 cover?
- The present invention relates to a process for the production of a dicarboxylic acid. The process comprises fermenting a yeast in the presence of a carbohydrate-containing substrate and low amounts of oxygen at a pH value at which at least 50% of the dicarboxylic acid is in the acid form. The process of the present invention allows for high yields of the dicarboxylic acid product and is more co…
- Who is the assignee on this patent?
- Jansen Mickel Leonardus August, Verwaal René, Dsm Ip Assets Bv
- What technology area does this patent fall under?
- Primary CPC classification C12P7/46. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 21 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).