Method for producing l-lysine using microorganisms having ability to produce l-lysine
US-2017145453-A1 · May 25, 2017 · US
Engineered microorganism producing homo-succinic acid and method for preparing succinic acid using the same
US9217138B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9217138-B2 |
| Application number | US-35932209-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 25, 2009 |
| Priority date | Jul 28, 2006 |
| Publication date | Dec 22, 2015 |
| Grant date | Dec 22, 2015 |
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Abstract
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The present invention relates to a mutant microorganism, which is selected from the group consisting of genus Mannheimia , genus Actinobacillus and genus Anaerobiospirillum , producing homo-succinic acid and a method for producing homo-succinic acid using the same, and more particularly to a mutant microorganism producing succinic acid at a high concentration while producing little or no other organic acids in anaerobic conditions, which is obtained by disrupting a gene encoding lactate dehydrogenase (ldhA), a gene encoding phosphotransacetylase (pta), and a gene encoding acetate kinase (ackA), without disrupting a gene encoding pyruvate formate lyase (pfl), as well as a method for producing succinic acid using the same. The inventive mutant microorganism has the property of having a high growth rate and succinic acid productivity while producing little or no organic acids, as compared to the prior strains producing succinic acid. Thus, the inventive mutant microorganism is useful to produce succinic acid for industrial use.
First claim
Opening claim text (preview).
What is claimed is: 1. A mutant rumen bacterium, said mutant rumen bacterium lacking (i) a lactate dehydrogenase gene (ldhA), (ii) a phosphotransacetylase gene (pta), and (iii) an acetate kinase gene (ackA), said mutant rumen bacterium comprising non-disrupted pyruvate formate-lyase gene (pfl), and said mutant rumen bacterium having the property of producing succinic acid in anaerobic conditions, wherein said rumen bacterium is selected from the group consisting of genus M…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C12N9/1217Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C12N1/20Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US9217138B2 cover?
- The present invention relates to a mutant microorganism, which is selected from the group consisting of genus Mannheimia , genus Actinobacillus and genus Anaerobiospirillum , producing homo-succinic acid and a method for producing homo-succinic acid using the same, and more particularly to a mutant microorganism producing succinic acid at a high concentration while producing little or no ot…
- Who is the assignee on this patent?
- Lee Sang Yup, Lim Sung Won, Song Hyohak, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification C12N9/1217. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Dec 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).