Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use

US8993248B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8993248-B2
Application numberUS-201213726219-A
CountryUS
Kind codeB2
Filing dateDec 23, 2012
Priority dateDec 31, 2011
Publication dateMar 31, 2015
Grant dateMar 31, 2015

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Abstract

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Vitamin D binding proteins (DBP), in particular truncated DBP and mutated, truncated DBP, as well as fusion proteins thereof, nucleic acid molecules encoding same, vectors, host cells, and methods, kits and solid supports for determining the total amount of 25-hydroxy vitamin D 2 and 25-hydroxy vitamin D 3 in a test sample.

First claim

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What is claimed is: 1. A truncated vitamin D binding protein (DBP) comprising an amino acid sequence that is at least 99% identical to the amino acid sequence set forth in SEQ ID NO: 12 or SEQ ID NO: 14 and in which amino acid 76, amino acid 79, or amino acids 76 and 79 are mutated to a different amino acid as compared to SEQ ID NO: 12 or SEQ ID NO: 14, wherein the truncated DBP has vitamin D binding activity. 2. The truncated DBP of claim 1 , wherein said trun…

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What does patent US8993248B2 cover?
Vitamin D binding proteins (DBP), in particular truncated DBP and mutated, truncated DBP, as well as fusion proteins thereof, nucleic acid molecules encoding same, vectors, host cells, and methods, kits and solid supports for determining the total amount of 25-hydroxy vitamin D 2 and 25-hydroxy vitamin D 3 in a test sample.
Who is the assignee on this patent?
Abbott Lab
What technology area does this patent fall under?
Primary CPC classification G01N33/82. Mapped technology areas include Physics.
When was this patent published?
Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).