Methods for quantifying vitamin D metabolites by mass spectrometry

US9201079B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9201079-B2
Application numberUS-201013503963-A
CountryUS
Kind codeB2
Filing dateOct 19, 2010
Priority dateOct 26, 2009
Publication dateDec 1, 2015
Grant dateDec 1, 2015

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Abstract

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Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise associating an amine with a dihydroxyvitamin D metabolite in a sample, ionizing the adduct, and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample.

First claim

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What is claimed is: 1. A method for quantifying the amount of a dihydroxyvitamin D metabolite in a sample, comprising the steps of: (a) combining a first sample comprising an amount of dihydroxyvitamin D metabolite with an amine selected from the group consisting of glycine, alanine, serine, arginine, thyroxine, triiodothyronine, diiodothyronine and iodothyronine, thereby forming a second sample comprising non-covalent adducts comprising the dihydroxyvitamin D metabolite and the…

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What does patent US9201079B2 cover?
Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise associating an amine with a dihydroxyvitamin D metabolite in a sample, ionizing the adduct, and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample.
Who is the assignee on this patent?
Soldin Steven J, Univ Georgetown
What technology area does this patent fall under?
Primary CPC classification G01N33/82. Mapped technology areas include Physics.
When was this patent published?
Publication date Tue Dec 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).