Compositions and methods for reducing methane emissions in ruminant populations
US-2024009291-A1 · Jan 11, 2024 · US
US8992989B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8992989-B2 |
| Application number | US-201414499462-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 29, 2014 |
| Priority date | Nov 17, 2006 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Pharmaceutical compositions of topiramate for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the compositions of which can be selectively adjusted, respectively, to release the active ingredient along a pre-determined release profile. Method of treating or preventing pathological disorders in mammalian subjects comprising the administration of the novel formulations disclosed herein is also provided.
Opening claim text (preview).
What is claimed is: 1. A sustained release formulation of topiramate comprising topiramate as an active ingredient, which is released immediately and continuously upon administration from the formulation, the formulation comprising: (a) an extended release (XR) topiramate-containing component, comprising a coating material selected from the group consisting of cellulosic polymers and acrylic polymers, and, optionally, (b) an immediate release (IR) topiramate-containing component…
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