Biomarkers and methods for measuring and monitoring inflammatory disease activity
US-2015377909-A1 · Dec 31, 2015 · US
US8990059B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8990059-B2 |
| Application number | US-201013500431-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 14, 2010 |
| Priority date | Oct 21, 2009 |
| Publication date | Mar 24, 2015 |
| Grant date | Mar 24, 2015 |
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The invention relates to a method and apparatus for obtaining information from an amplification curve of a target nucleic acid sequence or sequences by defining at least one model function that describes the amplification curve and that contains at least one parameter that is related to a physical quantity that influences the signals recorded, fitting said model function to the amplification curve, and obtaining information with respect to said physical quantity by identifying the value of said parameter that results in the best fit of the model function.
Opening claim text (preview).
The invention claimed is: 1. A computer implemented method for obtaining information for automatic quantification of nucleic acid sequences from an amplification curve of a target nucleic acid sequence obtained from an amplification reaction process, comprising the steps: (a) defining, using a computer, at least one model function that describes the amplification curve and that contains at least one parameter that is related to a physical quantity that has an impact on the signals…
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