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Biomarkers and methods for measuring and monitoring inflammatory disease activity
US9200324B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9200324-B2 |
| Application number | US-90598410-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 15, 2010 |
| Priority date | Oct 15, 2009 |
| Publication date | Dec 1, 2015 |
| Grant date | Dec 1, 2015 |
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Abstract
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Biomarkers useful for diagnosing and assessing inflammatory disease are provided, along with kits for measuring their expression. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples. The biomarkers include at least two biomarkers selected from the DAIMRK group and the score is a disease activity index (DAI).
First claim
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The invention claimed is: 1. A method for generating quantitative data for a first subject comprising: performing at least one immunoassay on a first sample from the first subject to generate a first dataset comprising the quantitative data, wherein the quantitative data represents at least twelve protein markers comprising: chitinase 3-like 1 (cartilage glycoprotein-39) (CHI3L1); C-reactive protein, pentraxin-related (CRP); epidermal growth factor (beta-urogastrone) (EGF); inte…
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Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Physics · mapped topic
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- What does patent US9200324B2 cover?
- Biomarkers useful for diagnosing and assessing inflammatory disease are provided, along with kits for measuring their expression. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples. The biomarkers include at least two biomarkers selected from the DAIMRK group a…
- Who is the assignee on this patent?
- Cavet Guy L, Shen Yijing, Knowlton Nicholas, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/6883. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Dec 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).