Prokaryotic xylose isomerase for the construction of xylose fermenting yeasts

US8986948B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8986948-B2
Application numberUS-200913001326-A
CountryUS
Kind codeB2
Filing dateJul 1, 2009
Priority dateJul 2, 2008
Publication dateMar 24, 2015
Grant dateMar 24, 2015

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Abstract

Official abstract text for this publication.

The present invention relates to the use of nucleic acid molecules coding for a bacterial xylose isomerase (XI), preferably coming from Clostridium phytofermentans , for reaction/metabolization, particularly fermentation, of recombinant microorganisms of biomaterial containing xylose, and particularly for the production of bioalcohols, particularly bioethanol, by means of xylose fermenting yeasts. The present invention further relates to cells, particularly eukaryotic cells, which are transformed utilizing a nucleic acid expression construct which codes for a xylose isomerase, wherein the expression of the nucleic acid expression construct imparts to the cells the capability to directly isomerize xylose into xylulose. Said cells are preferably utilized for reaction/metabolization, particularly fermentation, of biomaterial containing xylose, and particularly for the production of bioalcohols, particularly bioethanol. The present invention also relates to methods for the production of bioethanol, and to methods for the production of further metabolization products, comprising the metabolization of media containing xylose.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for the recombinant expression and production of xylose isomerase or for the conversion of xylose to xylulose by an isolated host cell, wherein said isolated host cell is a yeast cell or a filamentous fungal cell, and said method consists of transforming said host cell with a nucleic acid molecule comprising a nucleic acid sequence that encodes a Clostridium phytofermentans xylose isomerase (XI) and wherein said nucleic acid sequence comprise…

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Classifications

  • Cross-Sectional Technologies · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • C12N9/92Primary

    Chemistry & Metallurgy · mapped topic

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What does patent US8986948B2 cover?
The present invention relates to the use of nucleic acid molecules coding for a bacterial xylose isomerase (XI), preferably coming from Clostridium phytofermentans , for reaction/metabolization, particularly fermentation, of recombinant microorganisms of biomaterial containing xylose, and particularly for the production of bioalcohols, particularly bioethanol, by means of xylose fermenting yea…
Who is the assignee on this patent?
Brat Dawid, Boles Eckhard, Keller Marco, and 2 more
What technology area does this patent fall under?
Primary CPC classification C12N9/92. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Mar 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).