Atherosclerosis-targeted liposome nanocarrier delivery system and preparation method therefor
US-2024424132-A1 · Dec 26, 2024 · US
US8980926B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8980926-B2 |
| Application number | US-201013504635-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 28, 2010 |
| Priority date | Oct 30, 2009 |
| Publication date | Mar 17, 2015 |
| Grant date | Mar 17, 2015 |
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The present invention relates to methods of treating a subject with malaria comprising administering a 2-aminoindole compound represented by Formula: (I)—The values and preferred values of the variables in Structural Formula I are defined herein.
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What is claimed is: 1. A method of treating a subject with malaria, comprising administering to the subject in need thereof an effective amount of a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 and R 4 are independently hydrogen, halogen, (C 1 -C 4 )alkyl, or (C 1 -C 4 )alkoxy; R 5 is aryl, heteroaryl, cycl…
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