Method for providing diagnosis of cancer using seprase as a marker

US8980573B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8980573-B2
Application numberUS-79194610-A
CountryUS
Kind codeB2
Filing dateJun 2, 2010
Priority dateDec 10, 2007
Publication dateMar 17, 2015
Grant dateMar 17, 2015

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Abstract

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The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the human fibroblast activation protein (FAP/seprase) as a universal marker of different cancer types. Seprase aids in the assessment of pulmonary or lung cancer (LC) or of colon cancer, e.g., of non-small cell lung carcinoma (NSCLC) or colorectal cancer (CRC), but also likely of other specific types of cancer. Such specific cancer types are, e.g., esophagus, head and neck cancer, stomach cancer, bile duct cancer, pancreas cancer, kidney cancer, cervix cancer, ovary cancer, breast cancer, bladder cancer, endometrium cancer or prostate cancer. Furthermore, it especially relates to a method for assessing cancer from a liquid sample, derived from an individual by measuring seprase in said sample. Measurement of seprase can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery.

First claim

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What is claimed is: 1. A method for providing a diagnosis of cancer in a subject suspected of having at least one of lung cancer, colon cancer, esophageal cancer, head and neck cancer, stomach cancer, bile duct cancer, pancreatic cancer, kidney cancer, cervical cancer, ovarian cancer, breast cancer, bladder cancer, endometrial cancer and prostate cancer, comprising: contacting, in vitro, a portion of a sample selected from the group consisting of serum and plasma from a subject wi…

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What does patent US8980573B2 cover?
The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the human fibroblast activation protein (FAP/seprase) as a universal marker of different cancer types. Seprase aids in the assessment of pulmonary or lung cancer (LC) or of colon cancer, e.g., of non-small cell lung carcinoma (NSCLC) or colorectal cancer (CRC), but also likely of other specific…
Who is the assignee on this patent?
Rollinger Wolfgang, Karl Johann, Kochan Jarema Peter, and 3 more
What technology area does this patent fall under?
Primary CPC classification G01N33/5752. Mapped technology areas include Physics.
When was this patent published?
Publication date Tue Mar 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).