Engineered microorganism producing homo-succinic acid and method for preparing succinic acid using the same
US-9217138-B2 · Dec 22, 2015 · US
Engineered bacteria produce succinate from sucrose
US8962272B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8962272-B2 |
| Application number | US-201113696465-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 20, 2011 |
| Priority date | Jun 21, 2010 |
| Publication date | Feb 24, 2015 |
| Grant date | Feb 24, 2015 |
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Abstract
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Bacteria optimized to produce succinate and other feedstocks by growing on low cost carbon sources, such as sucrose.
First claim
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We claim: 1. A recombinant E. coli bacteria, comprising a. an overexpressed pyruvate carboxylase (pyc) activity, b. an added overexpressed scr operon containing scrA, scrB, scrK and scrY and scrR activities, c. deactivated acetate kinase (ack) or phosphotransacetylase (pta) or both ack-pta genes, d. deactivated repressor of aceBAK operon (iclR) genes, and i. deactivated alcohol dehydrogenase (adhE) and lactate dehydrogenase (ldhA) genes, or ii. deactivated succinate deh…
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Chemistry & Metallurgy · mapped topic
- C12P7/46Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US8962272B2 cover?
- Bacteria optimized to produce succinate and other feedstocks by growing on low cost carbon sources, such as sucrose.
- Who is the assignee on this patent?
- San Ka-Yiu, Bennett George N, Wang Jian, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification C12P7/46. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).