Compositions and methods for treatment of pouchitis

US8946178B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8946178-B2
Application numberUS-201113299291-A
CountryUS
Kind codeB2
Filing dateNov 17, 2011
Priority dateFeb 13, 2003
Publication dateFeb 3, 2015
Grant dateFeb 3, 2015

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

The present invention relates methods of treating pouchitis by administering a pharmaceutical formulation suitable for rectal use, such as an enema or suppository, comprising an antisense oligonucleotide targeted to ICAM-1 to an individual

First claim

Opening claim text (preview).

What is claimed is: 1. A method of treating pouchitis in a human, comprising: identifying a human having pouchitis; and rectally administering to said human a pharmaceutical composition, wherein said pharmaceutical composition comprises an antisense oligonucleotide that specifically hybridizes to and inhibits the activity of a human ICAM-1 mRNA, wherein said antisense oligonucleotide comprises from 16 to 20 phosphorothioate linked nucleosides that are each independently selected…

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What does patent US8946178B2 cover?
The present invention relates methods of treating pouchitis by administering a pharmaceutical formulation suitable for rectal use, such as an enema or suppository, comprising an antisense oligonucleotide targeted to ICAM-1 to an individual
Who is the assignee on this patent?
Wedel Mark K, Miner Phillip B, Isis Pharmaceuticals Inc
What technology area does this patent fall under?
Primary CPC classification A61K9/0031. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Feb 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).