Dual variable region antibody-like binding proteins having cross-over binding region orientation
US-9221917-B2 · Dec 29, 2015 · US
IL-1 binding proteins
US9303085B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9303085-B2 |
| Application number | US-201314104991-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 12, 2013 |
| Priority date | May 14, 2010 |
| Publication date | Apr 5, 2016 |
| Grant date | Apr 5, 2016 |
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Abstract
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Proteins that bind IL-1α and IL-1β are described along with their use in compositions and methods for treating, preventing, and diagnosing IL-1-related disorders and for detecting IL-1α and IL-1β in cells, tissues, samples, and compositions.
First claim
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What is claimed is: 1. An isolated nucleic acid molecule comprising a nucleotide sequence encoding a polypeptide chain amino acid sequence of a binding protein comprising first and second polypeptide chains, wherein said first polypeptide chain comprises a first VD1-(X1)n-VD2-C-(X2)n, wherein: VD1 is a first heavy chain variable domain; VD2 is a second heavy chain variable domain; C is a heavy chain constant domain; X1 is a linker with the proviso that it is not CH1; X2 is…
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Frequently asked questions
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- What does patent US9303085B2 cover?
- Proteins that bind IL-1α and IL-1β are described along with their use in compositions and methods for treating, preventing, and diagnosing IL-1-related disorders and for detecting IL-1α and IL-1β in cells, tissues, samples, and compositions.
- Who is the assignee on this patent?
- Abbvie Inc, Abbvie Inc
- What technology area does this patent fall under?
- Primary CPC classification C07K16/245. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).