Rosuvastatin calcium and process for producing intermediate thereof
US-2024360086-A1 · Oct 31, 2024 · US
Gene GMS 01
US8940503B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8940503-B2 |
| Application number | US-80162910-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 17, 2010 |
| Priority date | Sep 9, 2005 |
| Publication date | Jan 27, 2015 |
| Grant date | Jan 27, 2015 |
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Abstract
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The present invention relates to microorganisms genetically engineered to increase yield and/or efficiency of biomass production from a carbon source, such as e.g. glucose. Processes for generating such microorganisms are also provided by the present invention. The invention also relates to polynucleotide sequences comprising genes that encode proteins that are involved in the bioconversion of a carbon source such as e.g. glucose into biomass. The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. Also included are processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms leading to a microorganism with reduced carbon source diversion, i.e. higher yield and/or efficiency of biomass production from a carbon source such as e.g. glucose.
First claim
Opening claim text (preview).
The invention claimed is: 1. A process for the production of biomass from glucose comprising fermenting a recombinant microorganism selected from Gluconobacter oxydans , wherein the endogenous gene encoding membrane-bound glucose dehydrogenase is knocked-out in said microorganism, said microorganism producing at least 75% more biomass from glucose than the wild-type microorganism capable to express an endogenous membrane-bound glucose dehydrogenase after 24 hours in a bioconversio…
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Chemistry & Metallurgy · mapped topic
- C12N9/0006Primary
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US8940503B2 cover?
- The present invention relates to microorganisms genetically engineered to increase yield and/or efficiency of biomass production from a carbon source, such as e.g. glucose. Processes for generating such microorganisms are also provided by the present invention. The invention also relates to polynucleotide sequences comprising genes that encode proteins that are involved in the bioconversion of …
- Who is the assignee on this patent?
- Shinjoh Masako, Dsm Ip Assets Bv
- What technology area does this patent fall under?
- Primary CPC classification C12N9/0006. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jan 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).