Pharmaceutical composition comprising thrombolytic peptide-tetrahydroisoquinoline conjugate
US-12059448-B2 · Aug 13, 2024 · US
US8933015B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8933015-B2 |
| Application number | US-201313942501-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 15, 2013 |
| Priority date | Dec 10, 2010 |
| Publication date | Jan 13, 2015 |
| Grant date | Jan 13, 2015 |
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Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.
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What is claimed is: 1. A method for treating a viral infection caused by a Hepatitis C virus in a human patient comprising administering to the human patient in need thereof a therapeutically effective amount of a compound of Formula I: or a pharmaceutically acceptable salt or a pharmaceutical composition thereof, wherein: X 1 is O, S, or NR 1 ; each R 1 is i…
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