Electronic label-free dna and genome sequencing

US2022371012A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2022371012-A1
Application numberUS-202217879254-A
CountryUS
Kind codeA1
Filing dateAug 2, 2022
Priority dateFeb 9, 2016
Publication dateNov 24, 2022
Grant date

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A method of manufacturing a device useable in DNA or genome sequencing comprises disposing pairs of electrodes on a substrate, the electrodes within each pair separated by a nanogap; depositing a resist layer over the electrodes; patterning the resist layer to create an exposed region on each electrode at or near each nanogap; roughening the electrode surface within each exposed region using various methods; and exposing the exposed regions to biomolecules, wherein one biomolecule bridges each nanogap of each electrode pair, with each end of each biomolecule bound to the electrodes at each exposed region.

First claim

Opening claim text (preview).

We claim: 1 . A method of manufacturing a device for DNA or genome sequencing, said method comprising: disposing a pair of electrodes on a substrate, the electrodes separated by a nanogap; depositing a resist layer over the pair of electrodes; patterning the resist layer to create an exposed region on each electrode at or near the nanogap; exposing the electrodes to plasma etching or gold (Au) ion beam implantation to roughen the surface within each exposed region; and exposing the exposed regions to a biomolecule, wherein the biomolecule has at least first and second ends, with each end comprising a functionalization for bonding to the pair of electrodes, wherein the biomolecule bridges the nanogap, with the first and second ends of the biomolecule being bound to the exposed regions.

Assignees

Inventors

Classifications

  • on metallic substrates or on substrates of boron or silicon · CPC title

  • Electrodes · CPC title

  • characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces · CPC title

  • Ion implantation · CPC title

  • Nanoscaled · CPC title

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Frequently asked questions

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What does patent US2022371012A1 cover?
A method of manufacturing a device useable in DNA or genome sequencing comprises disposing pairs of electrodes on a substrate, the electrodes within each pair separated by a nanogap; depositing a resist layer over the electrodes; patterning the resist layer to create an exposed region on each electrode at or near each nanogap; roughening the electrode surface within each exposed region using va…
Who is the assignee on this patent?
Roswell Biotechnologies Inc
What technology area does this patent fall under?
Primary CPC classification C12Q1/6869. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Thu Nov 24 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).